{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:54:57Z","timestamp":1787838897130,"version":"build-2784847793"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T00:00:00Z","timestamp":1591574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To assess Uveitis\u2010Glaucoma\u2010Hyphaema syndrome (UGH syndrome) with focus on resolution, glaucoma development and risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective case\u2013control study with a cross\u2010sectional component was performed to compare three groups with 71 patients each: UGH syndrome, dislocated intraocular lens (IOL) without UGH syndrome and ordinary pseudophakia. Main outcome measures were resolution of the UGH syndrome, best\u2010corrected visual acuity (BCVA) and the need of glaucoma therapy. We also assessed the IOL\u2010iris contact signs and the use of blood thinners.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Uveitis\u2010Glaucoma\u2010Hyphaema (UGH) syndrome resolved in 77 % of patients who underwent various kind of IOL surgery. Intraocular pressure (IOP) decreased and BCVA improved in the operated cases (p\u00a0=\u00a00.02 and p\u00a0&lt;\u00a00.001, respectively), but not in the cases treated conservatively. Intraocular pressure (IOP) \u226522\u00a0mmHg at the first haemorrhage predicted the need of glaucoma therapy after UGH syndrome resolution (p\u00a0=\u00a00.002, area under the curve\u00a0=\u00a00.8). Fifty\u2010one per cent of patients without preexisting glaucoma needed glaucoma therapy after UGH syndrome resolution. Pseudophacodonesis was seen more frequently in the UGH group than in the ordinary pseudophakia group (p\u00a0=\u00a00.001). Iris defects were not more frequent in the UGH group than in the Dislocated group but the types of defects differed (p\u00a0&lt;\u00a00.0001). Blood thinners were not more frequent in UGH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In UGH syndrome, the results are better with surgical intervention than with conservative treatment, but surgery does not guarantee resolution. Pseudophacodonesis is a risk factor for UGH syndrome, but blood thinners are not, and iris defects are not specific to UGH syndrome. A high IOP at the first haemorrhage increases the risk for needing subsequent IOP\u2010lowering therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.14477","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T13:25:58Z","timestamp":1591622758000},"page":"69-74","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Seventy\u2010one cases of uveitis\u2010glaucoma\u2010hyphaema syndrome"],"prefix":"10.1111","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7601-3460","authenticated-orcid":false,"given":"Laura","family":"Armonaite","sequence":"first","affiliation":[{"name":"Department of Clinical Neuroscience Division of Ophthalmology and Vision St. Erik Eye Hospital Karolinska Institutet Stockholm 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