{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:29:50Z","timestamp":1792798190894,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T00:00:00Z","timestamp":1593129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"DOI":"10.13039\/100010810","name":"Eye Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100010810","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100013510","name":"Eye and Tissue Bank Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100013510","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Mary and Georg C. Ehrnrooths Foundation","id":[{"id":"https:\/\/ror.org\/01ddjva78","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Finnish Ophthalmological Society","id":[{"id":"https:\/\/ror.org\/05y3e7a78","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To analyse the prevalence, incidence and aetiology of paediatric uveitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective, population\u2010based cohort study of Finnish children with uveitis in Northern Ostrobothnia Hospital District in 2008\u20132017. The data included parameters for age, gender, age at diagnosis, laterality, chronicity, anatomical distribution of the disease, aetiology and systemic association.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One hundred fifty patients aged &lt;16\u00a0years (mean age 6.9\u00a0\u00b1\u00a03.9\u00a0years) with uveitis were included, out of whom 53% were girls. The first uveitis episode occurred at 1\u20136\u00a0years in 59%, and 62% of them were girls. In the age group of 7\u201315\u00a0years, boys were diagnosed with uveitis more frequently than girls (61% versus 39%, respectively). Seventy percent of the girls were diagnosed with their first uveitis episode at the age of 1\u20136\u00a0years, whereas only 48% of the boys were diagnosed at that age. The prevalence of uveitis increased from 64\/100\u00a0000 children &lt;16\u00a0years in 2008 (95% CI, 47.7\u201384.2) to 106\/100\u00a0000 in 2017 (95% CI, 84.6\u2013130.2). The incidence of childhood uveitis in 2008\u20132017 was 14\/100\u00a0000 person\u2010years in children &lt;16\u00a0years (95% CI, 11.3\u201316.5). Eighty\u2010seven percent of the cases were non\u2010infectious, 9% were infectious, and 3% had masquerade syndromes. Sixty\u2010one percent of patients had juvenile idiopathic arthritis (JIA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prevalence of paediatric uveitis has increased during the last decade in both genders. Uveitis is more frequent in girls, and they were diagnosed at a younger age than boys. Idiopathic cases and JIA accounted for a majority of aetiological features.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.14535","type":"journal-article","created":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T04:43:43Z","timestamp":1593233023000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Prevalence, incidence and epidemiology of childhood uveitis"],"prefix":"10.1111","volume":"99","author":[{"given":"Mira","family":"Siiskonen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Oulu University Hospital Oulu Finland"},{"name":"PEDEGO Research Unit Oulu Finland"},{"name":"Medical Research Center University of Oulu Oulu Finland"},{"name":"Division of Operative Care Oulu University Hospital Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iida","family":"Hirn","sequence":"additional","affiliation":[{"name":"PEDEGO Research Unit Oulu Finland"},{"name":"Medical Research Center University of Oulu Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roosa","family":"Pes\u00e4l\u00e4","sequence":"additional","affiliation":[{"name":"PEDEGO Research Unit Oulu Finland"},{"name":"Medical Research Center University of Oulu Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Hautala","sequence":"additional","affiliation":[{"name":"Research Unit of Biomedicine University of Oulu Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasi","family":"Ohtonen","sequence":"additional","affiliation":[{"name":"Medical Research Center University of Oulu Oulu Finland"},{"name":"Division of Operative Care Oulu University Hospital Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5454-5602","authenticated-orcid":false,"given":"Nina","family":"Hautala","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Oulu University Hospital Oulu Finland"},{"name":"PEDEGO Research Unit Oulu Finland"},{"name":"Medical Research Center University of Oulu Oulu Finland"},{"name":"Division of Operative Care Oulu University Hospital Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-019-1139-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.050609"},{"key":"e_1_2_5_4_1","first-page":"192","article-title":"Pediatric uveitis","volume":"7","author":"Chan NS","year":"2018","journal-title":"Asia Pac J Ophthalmol"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/09273948.2016.1167223"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2017.1305420"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2017.1420202"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2008.148015"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/09273948.2013.791701"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.03.057"},{"key":"e_1_2_5_11_1","first-page":"119","article-title":"A population\u2010based study on uveitis in juvenile rheumatoid arthritis","volume":"17","author":"Kotaniemi K","year":"1999","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(01)00773-4"},{"key":"e_1_2_5_13_1","first-page":"143","article-title":"The frequency and outcome of uveitis in patients with newly diagnosed juvenile idiopathic arthritis in two 4\u2010year cohorts from 1990\u20131993 and 2000\u20132003","volume":"32","author":"Kotaniemi K","year":"2014","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000501"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/09273948.2016.1160129"},{"key":"e_1_2_5_16_1","first-page":"281","article-title":"Clinical characteristics of juvenile idiopathic arthritis in an area of central Italy: a population\u2010based study","volume":"29","author":"Marzetti V","year":"2017","journal-title":"Ann Ig"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e3283641ede"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1977.tb01306.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/IIO.0b013e31817d740e"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-017-0195-8"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2000.078001084.x"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273940802702561"},{"key":"e_1_2_5_23_1","first-page":"390","article-title":": for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001","volume":"31","author":"Petty RE","year":"2004","journal-title":"J Rheumatol"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2013.816677"},{"key":"e_1_2_5_25_1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.4103\/0974-9233.186096","article-title":"Demographic and clinical features of pediatric uveitis at a tertiary referral center in Iran","volume":"23","author":"Rahimi M","year":"2016","journal-title":"Middle East Afr J Ophthalmol"},{"key":"e_1_2_5_26_1","first-page":"356","article-title":"Uveitis: report of a 10\u2010year survey in Northern Finland","volume":"10","author":"Saari M","year":"1975","journal-title":"Can J Ophthalmol"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.05.002"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2016.1269933"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.14535","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.14535","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aos.14535","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.14535","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T11:43:27Z","timestamp":1723117407000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.14535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,26]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/aos.14535"],"URL":"https:\/\/doi.org\/10.1111\/aos.14535","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,26]]},"assertion":[{"value":"2020-02-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}