{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T04:50:12Z","timestamp":1791607812917,"version":"4.3.4"},"reference-count":287,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T00:00:00Z","timestamp":1606003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Continuous\u2010wave cyclophotocoagulation (CW\u2010CPC) is often preferred to medical and surgical treatments for managing refractory glaucoma. This review summarizes diode CW\u2010CPC indications, history, histopathology, methods, efficacy and safety. It also provides an overview of the latest data available on micropulse transscleral laser treatment (MP\u2010TLT) that uses repetitive micropulses of diode laser energy in an off\u2010and\u2010on cyclical fashion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature review was conducted on transscleral CW\u2010CPC (CW\u2010TSCPC), endoscopic CPC (ECP) and MP\u2010TLT. Relevant series of adult and paediatric patients were included for assessing the procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Regarding CW\u2010TCPC, highly variable success rates are reported in the literature, depending on the definition of success, type of underlying glaucoma, energy settings, follow\u2010up duration and retreatment rates. CW\u2010CPC often needs to be repeated, especially in paediatric patients. CW\u2010CPC exposes to risks of inflammation and chronic ocular hypotony or phthisis with irreversible visual loss. CW\u2010TSCPC has mainly been used in very severe forms of glaucoma, in painful eyes with limited visual potential or after filtering surgery failure. Published data on ECP are more limited but overall good success rates have been reported. Through the direct visualization of the targeted ciliary body in anatomically abnormal eyes, ECP is the preferred surgical procedure in paediatric refractory glaucoma. Complication rates are relatively low after ECP; however, large studies with long\u2010term follow\u2010up are needed. ECP may be used in difficult, refractory cases, but it is often used earlier when combined with cataract surgery. Despite limited data on the exact mechanism of action of MP\u2010TLT and a lack of standardization of laser settings, the first data from heterogeneous case series shows that it has a similar efficacy and a better safety profile compared to CW\u2010TSCPC in the medium term.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although they may lead to sight\u2010threatening complications, both CW\u2010TSCPC and ECP seem effective. ECP appears to be superior to CW\u2010TSCPC in paediatric refractory glaucoma. Unlike ECP combined with cataract surgery, evidence supporting a wider use of CW\u2010TSCPC and MP\u2010TLT in earlier stages of neuropathy is lacking. While it now appears that the safety profile of MP\u2010TLT is superior to that of CW\u2010CPC, robust prospective comparative studies including homogeneous and well\u2010defined cohorts of patients are still needed to confirm an at least comparable efficacy in the long term.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.14661","type":"journal-article","created":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T09:49:12Z","timestamp":1606038552000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":79,"title":["An update on continuous\u2010wave cyclophotocoagulation (CW\u2010CPC) and micropulse transscleral laser treatment (MP\u2010TLT) for adult and paediatric refractory glaucoma"],"prefix":"10.1111","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0798-1353","authenticated-orcid":false,"given":"Soufiane","family":"Souissi","sequence":"first","affiliation":[{"name":"Department of Vitreoretinal Surgery Adolphe de Rothschild Foundation Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yannick","family":"Le Mer","sequence":"additional","affiliation":[{"name":"Department of Vitreoretinal Surgery Adolphe de Rothschild Foundation Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Metge","sequence":"additional","affiliation":[{"name":"Department of Pediatric Ophthalmology Adolphe de Rothschild Foundation Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Portmann","sequence":"additional","affiliation":[{"name":"Department of Pediatric Ophthalmology Adolphe de Rothschild Foundation Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Baudouin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology III Quinze\u2010Vingts Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Labb\u00e9","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology III Quinze\u2010Vingts Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Hamard","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology III Quinze\u2010Vingts Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001053"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.13328"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702342"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.79"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1992.01080180074031"},{"key":"e_1_2_8_7_1","first-page":"794","article-title":"Cyclocryotherapy in selected cases of congenital glaucoma","volume":"21","author":"Al Faran MF","year":"1990","journal-title":"Ophthalm Surg"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S226554"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2017.04.003"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-304257"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001435"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001529"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000000503"},{"key":"e_1_2_8_14_1","volume-title":"Preferred Practice Pattern\u00ae Guidelines. 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