{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T22:46:45Z","timestamp":1787698005878,"version":"build-2784847793"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T00:00:00Z","timestamp":1612224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["P30 EY026877"],"award-info":[{"award-number":["P30 EY026877"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To determine the effect of age on the reoperation rate in children undergoing exotropia surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a population\u2010based retrospective cohort study using claims data that included children\u00a0\u2264\u00a012\u00a0years who had undergone exotropia surgery as the first strabismus operation and had\u00a0\u2265\u00a03\u00a0years of continuous enrolment were selected from the Optum de\u2010identified Clinformatics Data Mart Database (2003\u20132019). Patient age at the first exotropia surgery was grouped into three categories; 0\u20133, 4\u20136, and 7\u201312\u00a0years. We assessed the sex, race, age, surgical methods, continuous enrolment period after the first surgery, and the time between the first surgery and reoperation. Cox regression analysis was used to estimate the risk of reoperation at different ages. The hazard ratio of reoperation in children undergoing exotropia surgery according to the age at the first exotropia surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 2015 children, 312 (15.5%) underwent one or more reoperations. A reoperation was more often performed for recurrent exotropia (<jats:italic>n<\/jats:italic>\u00a0=\u00a0231) than for consecutive esotropia (<jats:italic>n<\/jats:italic>\u00a0=\u00a081). The time between the first surgery and reoperation was shorter for reoperation for consecutive esotropia (376\u00a0days) than for recurrent exotropia (672\u00a0days) (p\u00a0&lt;\u00a00.001). Younger children showed a higher reoperation hazard ratio than older children (p\u00a0&lt;\u00a00.001). In reoperation for consecutive esotropia, the patients aged 0\u20133\u00a0years showed a high hazard ratio (2.82; 95% CI, 1.59\u20135.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children undergoing exotropia surgery at a younger age have a higher reoperation rate than those undergoing surgery at an older age.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14771","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T03:28:03Z","timestamp":1612582083000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effect of age on reoperation rate in children undergoing exotropia surgery"],"prefix":"10.1111","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2169-8770","authenticated-orcid":false,"given":"Hwan","family":"Heo","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Stanford University School of Medicine Palo Alto California USA"},{"name":"Department of Ophthalmology Chonnam National University Medical School and Hospital Gwangju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7555-0715","authenticated-orcid":false,"given":"Scott R.","family":"Lambert","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Stanford University School of Medicine Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(00)00623-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273970601026193"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2008.02.007"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(83)34412-2"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/0065955X.1988.11981779"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2008.06.001"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2016.3470"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2004.07.033"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000001245"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003737.pub2"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19971020)387:2<167::AID-CNE1>3.0.CO;2-Z"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2017.1337154"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2010.06.007"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(77)90385-3"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2019.12.008"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.04.024"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(83)34410-9"},{"key":"e_1_2_9_19_1","first-page":"356","volume-title":"Binocular vision and ocular motility: theory and management of strabismus","author":"Von Noorden GK","year":"2002"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.14771","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aos.14771","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.14771","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T19:52:46Z","timestamp":1693338766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.14771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,2]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/aos.14771"],"URL":"https:\/\/doi.org\/10.1111\/aos.14771","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,2]]},"assertion":[{"value":"2020-09-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}