{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T23:47:21Z","timestamp":1785800841822,"version":"3.56.0"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T00:00:00Z","timestamp":1620086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare two surgical treatment options for acute corneal hydrops in keratoconus: Mini\u2010DMEK versus predescemetal sutures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixteen patients were treated by either Mini\u2010Descemet membrane endothelial keratoplasty (Mini\u2010DMEK) (<jats:italic>n<\/jats:italic>\u2009=\u20097, group 1) or predescemetal sutures (<jats:italic>n<\/jats:italic>\u2009=\u20099, group 2) early after onset of acute hydrops. Visual acuity, maximum corneal thickness (SD\u2010OCT) in the affected oedematous area, complications and recurrence rates were retrospectively compared between both groups. Measurements were taken immediately preoperatively as well as 1\u2009day, 1\u2009week and 1\u2009month postoperatively (Table\u20091).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both groups showed reductions in corneal thickness and increased visual acuity shortly after surgery. In group 1 (average age 33\u2009years\u2009\u00b1\u20097\u2009years), the best corrected visual acuity (BCVA) increased from logMAR 1.65\u2009\u00b1\u20090.7 before Mini\u2010DMEK to logMAR 0.93\u2009\u00b1\u20090.6 30\u2009days after Mini\u2010DMEK (p\u2009=\u20090.046). During that period, maximum corneal thickness decreased from 1159\u2009\u00b1\u2009338\u2009\u00b5m before surgery to 531\u2009\u00b1\u200975\u2009\u00b5m after Mini\u2010DMEK (p\u2009=\u20090.046). Patients from group 2 (average age 34\u2009\u00b1\u200910\u2009years) had a BCVA of logMAR 1.59\u2009\u00b1\u20090.8 which increased to logMAR 0.97\u2009\u00b1\u20090.5 (p\u2009=\u20090.014) 30\u2009days after surgery. At the same time, the preoperative maximum corneal thickness decreased from 1439\u2009\u00b1\u2009272\u2009\u00b5m to 476\u2009\u00b1\u2009162\u2009\u00b5m (p\u2009=\u20090.014). There was no difference in corneal thickness or BCVA one month after the surgical intervention between both groups (p\u2009=\u20090.394 and p\u2009=\u20090.871).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both techniques, Mini\u2010DMEK and predescemetal sutures, are effective in the treatment of an acute hydrops in keratoconus. Mini\u2010DMEK appears to be beneficial in large DM tears.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14835","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T13:12:48Z","timestamp":1620133968000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Comparison of Mini\u2010DMEK versus predescemetal sutures as treatment of acute hydrops in keratoconus"],"prefix":"10.1111","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9836-8214","authenticated-orcid":false,"given":"Alexander","family":"H\u00e4ndel","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Faculty of Medicine and University Hospital Cologne University of Cologne Cologne 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