{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:49:52Z","timestamp":1789681792223,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T00:00:00Z","timestamp":1625616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008218","name":"Gangstedfonden","doi-asserted-by":"publisher","award":["A33352"],"award-info":[{"award-number":["A33352"]}],"id":[{"id":"10.13039\/501100008218","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005860","name":"Helsefonden","doi-asserted-by":"publisher","award":["20\u2010B\u20100169"],"award-info":[{"award-number":["20\u2010B\u20100169"]}],"id":[{"id":"10.13039\/501100005860","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate the efficacy of myopia control defined by axial elongation and safety of orthokeratology lenses (OKL) in a Scandinavian (Danish) population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sixty Danish children aged 6\u201312\u2009years with myopia ranging from 0.5 to 4.75 dioptres (D) spherical component and refractive astigmatism \u22642.5 D in both eyes were randomly assigned to either OKL or single\u2010vision spectacles (SVS). Study duration was 18\u2009months. Outcome measures were axial length (AL) measured with Lenstar LS900 (Haag\u2010Streit, Koeniz, Switzerland) and adverse events graded with Efron Grading Scale for Contact Lens Complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nineteen participants completed the 18\u2010month follow\u2010up in the OKL group and 28 in the SVS group. The average AL elongation in the OKL group was 0.24\u2009mm smaller as compared to the SVS group (95% confidence interval 0.12\u20130.36, mixed model adjusted for baseline sex, age and AL). There were no fast progressors (&gt;0.75 D\/year) in the OKL group during the follow\u2010up period in contrast to 22% in the SVS group. No treatment\u2010requiring or vision\u2010threatening adverse events were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Orthokeratology lenses reduced AL elongation in myopic Scandinavian children by 59%, with no treatment\u2010requiring or vision\u2010threatening adverse events. The results align with outcomes of previous clinical trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.14911","type":"journal-article","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T15:50:23Z","timestamp":1625673023000},"page":"175-182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Control of myopia using orthokeratology lenses in Scandinavian children aged 6 to 12 years. Eighteen\u2010month data from the Danish Randomized Study: Clinical study Of Near\u2010sightedness; TReatment with Orthokeratology Lenses (CONTROL study)"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4496-2610","authenticated-orcid":false,"given":"Trine Moldrup","family":"Jakobsen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology University Hospital of Southern Denmark Vejle Hospital Vejle Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flemming","family":"M\u00f8ller","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology University Hospital of Southern Denmark Vejle Hospital Vejle 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