{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T06:59:50Z","timestamp":1777100390534,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T00:00:00Z","timestamp":1624579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of the present study was to investigate photophobia and disability glare in adult patients with Marfan syndrome (MFS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this case\u2013control study, 44 patients with MFS (87\u2009eyes) were compared to 44 controls (88\u2009eyes), who were matched for age and sex. The subjects were asked to grade their photophobia and glare using 10\u2010cm visual analogue scales (VAS), which were marked with \u2018never\u2019 at zero and \u2018always\u2019 at 10\u2009\u2010cm. In addition, disability glare was measured with C\u2010Quant straylight meter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patients with MFS had significantly higher VAS scores than the controls in four out of seven statements related to photophobia and glare. When including cataract, spherical equivalent, iris colour, axial length and corneal curvature, three of the seven statements were still significantly different between the two groups. The mean straylight values were 1.29\u2009\u00b1\u20090.03 log(s) in the MFS group and 1.01\u2009\u00b1\u20090.03 log(s) in the control group (p\u2009&lt;\u20090.001, mixed model). These differences remained significant after adjusting for cataract, spherical equivalent, iris colour, axial length and corneal curvature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with MFS reported more photophobia and had a higher straylight value than the control group. Awareness of these findings of more photophobia and glare in the MFS patients is important when counselling and treating these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14935","type":"journal-article","created":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T05:04:01Z","timestamp":1624683841000},"page":"337-343","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Photophobia and disability glare in adult patients with Marfan syndrome: a case\u2013control study"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5351-6834","authenticated-orcid":false,"given":"Gunhild Falleth","family":"Sandvik","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Oslo University Hospital  Oslo Norway"},{"name":"Institute of Clinical Medicine University of Oslo  Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svend","family":"Rand\u2010Hendriksen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine University of Oslo  Oslo Norway"},{"name":"TRS National Resource Centre for Rare Disorders Sunnaas Rehabilitation Hospital  Nesodden Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liv","family":"Drolsum","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Oslo University Hospital  Oslo Norway"},{"name":"Institute of Clinical Medicine University of Oslo  Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3390-9811","authenticated-orcid":false,"given":"Olav","family":"Kristianslund","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Oslo University Hospital  Oslo Norway"},{"name":"Institute of Clinical Medicine University of Oslo  Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-018-0864-0"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2006.00860.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000000766"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01822.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.12681"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19960424)62:4<417::AID-AJMG15>3.0.CO;2-R"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0b013e3182474548"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12448"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-0690"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S224970"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183370"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1069609"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2011.07.001"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(89)80004-5"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12068"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.10.035"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.11.023"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(51)91866-1"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2009.072785"},{"key":"e_1_2_5_21_1","first-page":"684","article-title":"The eye in the Marfan syndrome","volume":"79","author":"Maumenee IH","year":"1981","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.05.020"},{"key":"e_1_2_5_23_1","unstructured":"NHS S(2021):Medical Information Document On Marfan's Syndrome."},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-012-2006-8"},{"key":"e_1_2_5_25_1","unstructured":"Online Mendelian Inheritance in Man O Fibrillin 1; FBN1 134797. 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