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Unused lenses (<jats:italic>n<\/jats:italic>\u2009=\u20095) and lenses (<jats:italic>n<\/jats:italic>\u2009=\u20094) from patients with no eye drop treatment were analysed as reference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The treated contact lenses displayed ruptured surfaces in comparison with unused and reference lenses. Dexamethasone and BAK were not detected in any of the lenses. A polyethylene oxide component was found in the treated lenses, likely originating from the dexamethasone eye drops or the contact lens solution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Dexamethasone and BAK do not accumulate in the contact lenses, and a depot effect of any clinical significance is unlikely. Therefore, the number of drops given after surgery should remain the same regardless of whether the child has contact lenses. The ruptured surface may both decrease the child\u2019s comfort and increase the risk of microbial adhesion, and so it is recommended that contact lenses should be replaced once a month throughout the course of anti\u2010inflammatory eye drop treatment after surgery for congenital cataract.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15003","type":"journal-article","created":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T13:05:23Z","timestamp":1629205523000},"page":"462-467","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rupture and chemical accumulation in contact lenses with dexamethasone eye drop administration after congenital cataract surgery"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3960-9537","authenticated-orcid":false,"given":"Sara","family":"De Lima","sequence":"first","affiliation":[{"name":"Division of Eye and Vision Karolinska Institute Stockholm 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