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These may be attributed to a breakdown of regulatory processes in the retina. Retinal venous oxygen saturation (SvO<jats:sub>2<\/jats:sub>) and arteriovenous difference in eyes with central RVO have been found to be reduced and elevated, respectively. The literature indicates variable and contradictory findings in regard to branch RVO and retinal oxygenation. Additionally, ischaemic eyes have been found to have elevated retinal arterial oxygen saturation; however, the literature reports variable results regarding SvO<jats:sub>2<\/jats:sub> levels. Medications have been suggested to increase SvO<jats:sub>2<\/jats:sub> in RVO eyes, which may represent an important mechanism for disease management. Ranibizumab is currently the most studied drug for retinal oxygenation in RVO and has been suggested to increase SvO<jats:sub>2<\/jats:sub> in RVO eyes. In comparison, dexamethasone was found to decrease SvO<jats:sub>2<\/jats:sub>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The current literature on retinal oxygenation in ischaemic subtypes of RVO and in drug therapies is minimal, and further work is required to expand upon our understanding of how ischaemia and drugs influence retinal oxygenation and clinical outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15066","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T16:08:51Z","timestamp":1638288531000},"page":"624-631","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical implications of retinal oximetry in retinal vein occlusion: a review"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2247-6942","authenticated-orcid":false,"given":"Aditya 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