{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:34:40Z","timestamp":1792802080492,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T00:00:00Z","timestamp":1643155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study examined the perioperative factors affecting surgical success in <jats:italic>ab interno<\/jats:italic> microhook trabeculotomy (\u03bcTLO).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 146 consecutive patients who underwent \u03bcTLO were included in this retrospective study. We performed Cox proportional hazard modelling by setting surgical success at 1\u2009year as an objective variable. The explanatory variables included age, sex, glaucoma type, preoperative intraocular pressure (IOP), glaucoma drug score, mean deviation (MD) of the Humphrey visual field test, duration of glaucoma drug use, antithrombotic drug use, combined cataract surgery, incision range and diabetes mellitus. Additionally, we performed 1:1 matching using propensity score analysis and compared the perioperative parameters between durations of glaucoma drug use of &lt;4.5\u2009years and\u2009\u2265\u20094.5\u2009years (50 patients each). We defined surgical success as satisfaction of all three criteria: IOP 5\u201321\u2009mmHg, IOP reduction of \u226520% from the preoperative IOP and no additional glaucoma surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The Cox proportional hazard model revealed that a longer duration of anti\u2010glaucoma medication was significantly associated with surgical failure. Propensity score matching analysis showed that the &lt;4.5\u2010year users of anti\u2010glaucoma drugs had significantly higher success rates than the \u22654.5\u2010year users (72% versus 52%; p\u2009=\u20090.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prolonged use of multiple glaucoma drugs adversely affected the outcome of \u03bcTLO at least at 1\u2009year postoperatively.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15090","type":"journal-article","created":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T15:04:45Z","timestamp":1643209485000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Association of the prolonged use of anti\u2010glaucoma medications with the surgical failure of <i>ab interno<\/i> microhook trabeculotomy"],"prefix":"10.1111","volume":"100","author":[{"given":"Mina","family":"Okuda","sequence":"first","affiliation":[{"name":"Division of 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