{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T13:36:27Z","timestamp":1789133787167,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100016275","name":"Seoul National University Bundang Hospital","doi-asserted-by":"publisher","award":["18\u20102018\u2010024"],"award-info":[{"award-number":["18\u20102018\u2010024"]}],"id":[{"id":"10.13039\/100016275","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate long\u2010term visual outcomes of patients with polypoidal choroidal vasculopathy (PCV) and typical neovascular age\u2010related macular degeneration (nAMD) in the real\u2010world setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective, multicenter, noninterventional consecutive cohort study. Two hundred eighty\u2010five eyes of 261 patients with PCV and 902 eyes of 877 patients with typical nAMD, who could be followed up 1\u2009year or longer from 2005 to 2018, were included. Mean changes in best\u2010corrected visual acuity (BCVA) from baseline in the PCV and the typical nAMD groups were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean follow\u2010up period of total patients was 4.3\u2009\u00b1\u20092.8 (1\u201310) years. Baseline BCVA was better in the PCV group than that in the typical nAMD group (0.59\u2009\u00b1\u20090.52 versus 0.79\u2009\u00b1\u20090.63 logMAR, p\u2009&lt;\u20090.001). The mean changes in BCVA from baseline in the PCV and nAMD group were +2.1 and \u22120.1 letters at 1\u2009year, \u22120.2 and \u22123.7 letters at 3\u2009years, \u22123.9 and \u221210.5 letters at 5\u2009years and\u2009\u2212\u20098.7 and\u2009\u2212\u200912.1 letters at 7\u2009years, respectively. Before 2006, the initial BCVA was sustained for approximately 1\u2009year in eyes with PCV and for less than half year in eyes with typical nAMD. However, after 2007, when anti\u2010VEGF agents were available, the initial BCVA was sustained for 4\u2009years in eyes with PCV, while it was sustained for 1\u2009year in eyes with typical nAMD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the real\u2010world, long\u2010term BCVA deteriorated in both PCV and typical nAMD groups, but the PCV group showed better visual outcomes than the typical nAMD group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15149","type":"journal-article","created":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T13:59:49Z","timestamp":1648821589000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of visual outcomes of polypoidal choroidal vasculopathy and typical neovascular age\u2010related macular degeneration\u2014up to 10\u2009years of follow\u2010up"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1664-7605","authenticated-orcid":false,"given":"Jun Young","family":"Park","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam South Korea"},{"name":"Department of Ophthalmology Uijeongbu Eulji Medical Center, Eulji University School of Medicine  Uijeongbu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5392-3667","authenticated-orcid":false,"given":"Young Joo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam South Korea"},{"name":"Department of Ophthalmology Kangwon National University Hospital, Kangwon National University Graduate School of Medicine  Chuncheon South 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