{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:57:30Z","timestamp":1789588650733,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T00:00:00Z","timestamp":1651276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81670884"],"award-info":[{"award-number":["81670884"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81873684"],"award-info":[{"award-number":["81873684"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study was to determine risk factors affecting changes in posterior corneal elevation (PCE) and predict the 5\u2010year stability after small incision lenticule extraction (SMILE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective, longitudinal study enrolled 161 patients post\u2010SMILE. The PCE values were measured at the apex, thinnest, maximal and 24 other prespecified preoperative points and at 6\u2009months, 1\u2009year and 5\u2009years postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Posterior corneas exhibited time\u2010dependent, region\u2010dependent and angle\u2010dependent changes. For every dioptre increase in the absolute preoperative spherical equivalent (SE), 10\u2010\u03bcm decrease in the central corneal thickness (CCT), 10\u2010\u03bcm increase in the maximum lenticule thickness (MLT), 10\u2010\u03bcm decrease in the residual bed thickness (RBT), 10% increase in the percentage ablation depth (PAD, MLT divided by CCT) and 10% decrease in the percentage stromal bed thickness (PSBT, RBT divided by CCT), PCE exhibited average forward displacements of 0.2\u20130.4, 0.2\u20130.7, 0.1\u20130.2, 0.1\u20130.3, 0.6\u20131.0 and 0.5\u20131.1\u2009\u03bcm, respectively (p\u2009&lt;\u20090.05). PSBT was the variable with the highest accuracy in predicting 5\u2010year stability of posterior corneas (area under curve\u2009=\u20090.75). The cut\u2010off values of SE, CCT, MLT, RBT, PAD and PSBT for increased PCE were \u22128.00 to \u22128.31 D, 481.0\u2013498.5\u2009\u03bcm, 139.5\u2013144.5\u2009\u03bcm, 255.5\u2013263.5\u2009\u03bcm, 26.9\u201328.3% and 48.9\u201352.6%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Eyes with thinner corneas, higher myopia requiring greater MLT and lower RBT exhibited greater predispositions towards posterior protrusion. The thresholds for preventing forward posterior corneal displacement were 26.9\u201328.3% for PAD and 48.9\u201352.6% for PSBT. Prediction of posterior corneal stability is useful for assessing surgical risks post\u2010SMILE.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15166","type":"journal-article","created":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T11:53:06Z","timestamp":1651319586000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Predictive factors of posterior corneal shift after\u00a0small incision lenticule extraction: a 5\u2010year follow\u2010up study"],"prefix":"10.1111","volume":"100","author":[{"given":"Huazheng","family":"Cao","sequence":"first","affiliation":[{"name":"Clinical College of Ophthalmology Tianjin Medical University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Clinical College of Ophthalmology Tianjin Medical University  Tianjin China"},{"name":"Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin Eye Institute Nankai University Affiliated Eye Hospital  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Liang","sequence":"additional","affiliation":[{"name":"Clinical College of Ophthalmology Tianjin Medical University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Clinical College of Ophthalmology Tianjin Medical University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4429-2004","authenticated-orcid":false,"given":"Vishal","family":"Jhanji","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology University of Pittsburgh School of Medicine  Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1257-6635","authenticated-orcid":false,"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Clinical College of Ophthalmology Tianjin Medical University  Tianjin China"},{"name":"Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin Eye Institute Nankai University Affiliated Eye Hospital  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00502-9"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2008.01821.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.10.011"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.02.020"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-20011101-05"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2006.03.015"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S84354"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000408"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000662"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1076\/soph.18.1.17.14070"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2019.07.037"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40662-020-00218-y"},{"key":"e_1_2_5_14_1","first-page":"104","article-title":"Relation between corneal biomechanical alteration after small incision lenticule extraction and intraoperative cutting thickness. 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