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Each participant underwent detailed ocular examinations at baseline and follow\u2010up. Data of AL, refraction error, PPA area, BMOD, BL, BTA and mChT were measured individually. Incident decreased mChT was defined as follow\u2010up mChT\u2009of\u2009participants decreased into the lowest quartile of baseline mChT.<\/jats:p><\/jats:sec>Results<\/jats:title>Subjects with longer AL, longer BMOD were more likely to have incident decreased mChT (odds ratio [OR], 1.56; 2.09, respectively, per 1 Z\u2010score increment), whereas larger BTA was less likely to develop decreased mChT (odds ratio [OR], 0.51, per 1 Z\u2010score increment). The area under the receiver operating curve (AUROC) of basic risk model for incident decreased mChT was 0.6284. After adding BMOD, BTA and AL separately to the basic risk model, the AUROC of the combination could reach 0.6967, 0.6944 and 0.7383, respectively. After combining BMOD, BTA and AL to the basic model, the AUROC of the combination showed the highest AUROC of 0.7608.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Bruch\u2019s membrane opening distance and AL are significant risk factors for incident decreased mChT, whereas BTA played protective role in the deterioration of mChT. In addition, a combination of BMOD, BTA and AL could serve as earlier predictors of the attenuation of mChT in myopia progression.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15187","type":"journal-article","created":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T07:14:42Z","timestamp":1653462882000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Morphological characteristics of the optic nerve head and impacts on longitudinal change in macular choroidal thickness during myopia progression"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2037-0677","authenticated-orcid":false,"given":"Guangyi","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"},{"name":"Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center 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