{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:49:25Z","timestamp":1781743765894,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T00:00:00Z","timestamp":1656115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004786","name":"ODAS Stichting","doi-asserted-by":"publisher","award":["2016\u201002 NEDROP2"],"award-info":[{"award-number":["2016\u201002 NEDROP2"]}],"id":[{"id":"10.13039\/501100004786","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Evaluate possibilities to reduce the number of infants screened for retinopathy of prematurity (ROP) and investigate costs and number of infants detected of current and alternative screening strategies in the Netherlands.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective population\u2010based study including clinical data from all infants born in 2017 and referred for ROP screening (NEDROP\u20102 study). Cost and effects of screening strategies were evaluated that differed on the criteria gestational age (GA), birth weight (BW) and presence of one or more specific risk factor(s) (RF): mechanical ventilation, sepsis, necrotizing enterocolitis, postnatal corticoids and\/or hypotension treated with inotropic agents. RF obtained from the Dutch perinatal registry (Perined).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the possible efficient strategies, the annual costs varied from \u20ac137\u2009966 (inclusion of BW\u2009&lt;\u2009700, 63 infants eligible for screening, detection of 17\/39 treated ROP) to \u20ac492\u2009689 (GA\u2009&lt;\u200930\u2009weeks <jats:italic>and<\/jats:italic> BW\u2009&lt;\u20091250\u2009grams, together with infants with GA 30\u201332 and BW 1250\u20131500 grams with presence of one more RF, 744 infants eligible for screening, all treated infants detected). Total annual costs of the current Dutch guideline that detects all infants that need treatment for ROP amount to \u20ac552\u2009143).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The current Dutch ROP guideline can be improved by implementing new screening inclusion criteria. The most effective strategy detecting all severe and treated infants, reduces the number of screened infants by 24% compared to the current guideline and the overall annual costs by \u20ac59454.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15205","type":"journal-article","created":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T07:44:27Z","timestamp":1656143067000},"page":"81-90","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cost reduction in screening for retinopathy of prematurity in the Netherlands by comparing different screening strategies"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0666-6746","authenticated-orcid":false,"given":"Kasia","family":"Trzcionkowska","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicoline E.","family":"Schalij\u2010Delfos","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elske M. E.","family":"van den Akker\u2010van Marle","sequence":"additional","affiliation":[{"name":"Department of Biomedical Data Sciences, Unit Medical Decision Making Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2008.10.014"},{"key":"e_1_2_7_3_1","first-page":"791","article-title":"Restricted universal guidelines for ROP screening: a possible misguidance for middle income countries","volume":"40","author":"Erdeve \u00d6.","year":"2010","journal-title":"Turkish Journal of Medical Sciences"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2018-3061"},{"key":"e_1_2_7_5_1","first-page":"233","article-title":"Final results of the early treatment for retinopathy of prematurity (ETROP) randomized trial","volume":"102","author":"Good W.V.","year":"2004","journal-title":"Transactions of the American Ophthalmological Society"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60178-6"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2019-314874"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.7.991"},{"key":"e_1_2_7_9_1","unstructured":"Institute for Medical Technology Assessment Calculator. Available at:www.imta.nl\/idbc"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187477"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2018.04.002"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0b013e318225a332"},{"key":"e_1_2_7_13_1","unstructured":"NEDROP. (2009) Available at:http:\/\/www.nedrop.nl\/richtlijnen\u2010en\u2010folders"},{"key":"e_1_2_7_14_1","unstructured":"Perined. (2017) Available at:https:\/\/www.perined.nl\/onderwerpen\/publicaties\u2010perined\/jaarboek\u2010zorg"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40942-019-0203-x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000356561"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-4182(00)80077-0"},{"key":"e_1_2_7_18_1","first-page":"730","article-title":"Screening and treatment in retinopathy of prematurity","volume":"112","author":"Stahl A.","year":"2015","journal-title":"Deutsches Arzteblatt International"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19990330)18:6<681::AID-SIM71>3.0.CO;2-R"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12798"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-303123"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.11.015"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-304493"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.128"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.15205","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aos.15205","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.15205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T13:01:00Z","timestamp":1692536460000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.15205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,25]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1111\/aos.15205"],"URL":"https:\/\/doi.org\/10.1111\/aos.15205","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,25]]},"assertion":[{"value":"2021-05-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}