{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T05:29:21Z","timestamp":1791437361927,"version":"4.3.3"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T00:00:00Z","timestamp":1675728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The literature on retinal vascular occlusions in Beh\u00e7et disease (BD) patients is limited. The aim of this study is to thoroughly investigate retinal vascular occlusions among ocular BD patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective, multicentre case\u2013control study. Three\u2010hundred and three eyes of 175 patients with ocular BD, from 13 hospitals in Israel and Palestine, were included. Patients were assigned into two groups according to the presence of retinal vascular occlusion. Epidemiology, systemic and ocular manifestations, treatments and outcomes were compared between the groups and risk factors for retinal vascular occlusions were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred twenty\u2010five patients (71.4%) were male. The mean age at presentation was 28.2\u2009\u00b1\u20090.86\u2009years. Retinal vascular occlusions were found in 80 eyes of 54 (30.9%) patients, including branch retinal vein occlusion (51.3%), peripheral vessels occlusions (32.5%), central retinal vein occlusion (13.8%) and arterial occlusions (7.5%). Systemic manifestations were similar among both groups. Anterior uveitis was more common in non\u2010occlusive eyes (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Non\u2010occlusive retinal vasculitis (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.03) and ocular complications were more common in occlusive eyes (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Treatments including mycophenolate mofetil, Infliximab or a combination therapy of anti\u2010metabolite and calcineurin inhibitor were more commonly used by occlusive patients (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Occlusive patients underwent more cataract surgeries (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.03). The occlusive group had worse mean best\u2010corrected visual acuity (BCVA) throughout follow\u2010up (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Risk factors for retinal vascular occlusions included male sex and Jewish ethnicity (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Retinal vascular occlusions were found in a third of ocular BD patients. Occlusive eyes had a worse prognosis. Risk factors for vascular occlusions were identified.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15645","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T05:10:06Z","timestamp":1675833006000},"page":"619-626","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Retinal vascular occlusions in ocular Beh\u00e7et disease \u2013 a comparative analysis"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7128-3288","authenticated-orcid":false,"given":"Michael","family":"Ostrovsky","sequence":"first","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Ramon","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Division of Ophthalmology Tel Aviv Sourasky Medical Center  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