{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T22:47:11Z","timestamp":1784328431406,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T00:00:00Z","timestamp":1684454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004331","name":"Johnson and Johnson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the effect of vectored thermal pulsation therapy (VTPT) on the repeatability of biometry readings of two different optical biometers in patients with meibomian gland dysfunction (MGD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients affected by MGD were included in this prospective, randomized, controlled, investigator\u2010masked study. One eye was randomized to VTPT (LipiFlow\u00ae, Johnson &amp; Johnson), and the contralateral eye served as a control. Three visits were scheduled at baseline, 2\u2009weeks and 3 months after the treatment. The main outcome parameter of the study was the repeatability of three calculations of emmetropic intraocular lens power (EIOLP) at the 3 months visit as compared to baseline using an optical biometer (IOLMaster\u00ae 700, Carl Zeiss Meditec AG). Repeatability of different keratometry values obtained by the optical biometer and a Placido\u2010disc topographer (MS\u201039\u00ae, CSO) served as secondary outcome parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010nine patients were included in the final analysis. While tear film parameters improved in the study eyes, there were no significant differences regarding the repeatability of three EIOLP measurements between baseline and 3\u2010months\u2010visit in both eyes (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05) and keratometry measurements in both the optical biometer and the Placido\u2010disc topographer. Remarkably, throughout all study visits, there were some outliers regarding the repeatability of measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>While both devices showed high repeatability regarding EIOLP and keratometry, future studies are needed to detect high\u2010risk patients for poor repeatability.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15711","type":"journal-article","created":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T10:09:11Z","timestamp":1684490951000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Repeatability of biometry in patients with meibomian gland dysfunction before and after vectored thermal pulsation therapy: A randomized, controlled trial"],"prefix":"10.1111","volume":"102","author":[{"given":"Andreas","family":"Schlatter","sequence":"first","affiliation":[{"name":"VIROS \u2013 Vienna Institute for Research in Ocular Surgery Karl Landsteiner Institute Hanusch Hospital  Vienna Austria"},{"name":"Department of Clinical Pharmacology Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0100-9862","authenticated-orcid":false,"given":"Stefan","family":"Palkovits","sequence":"additional","affiliation":[{"name":"VIROS \u2013 Vienna Institute for Research in Ocular Surgery Karl Landsteiner Institute Hanusch Hospital  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Ruiss","sequence":"additional","affiliation":[{"name":"VIROS \u2013 Vienna Institute for Research in Ocular Surgery Karl Landsteiner Institute Hanusch Hospital  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreea\u2010Dana","family":"Fisus","sequence":"additional","affiliation":[{"name":"VIROS \u2013 Vienna Institute for Research in Ocular Surgery Karl Landsteiner Institute Hanusch Hospital  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nino","family":"Hirnschall","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry Kepler University Hospital GmbH  Linz Austria"},{"name":"Johannes Kepler University Linz Medical Faculty  Linz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5664-7768","authenticated-orcid":false,"given":"Doreen","family":"Schmidl","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5547-5669","authenticated-orcid":false,"given":"Gerhard","family":"Garh\u00f6fer","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Findl","sequence":"additional","affiliation":[{"name":"VIROS \u2013 Vienna Institute for Research in Ocular Surgery Karl Landsteiner Institute Hanusch Hospital  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2015-307779"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001208"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2019.02.024"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S109663"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200310000-00008"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2017.10.050"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2017.05.008"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjo.10179"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2015.01.016"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S280868"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2011.631721"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S325659"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000002328"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-021-02129-5"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181814cff"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318239aaea"},{"key":"e_1_2_7_19_1","unstructured":"Matossian C.(2019)Effect of thermal pulsation system treatment on Keratometry measurements prior to cataract surgery. 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