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IOP was measured just before LTP and repeatedly during the 60\u2010month study period. Our previous report on 12\u2009months follow\u2010up data revealed no effect of LTP in eyes having an IOP &lt;15\u2009mmHg before the laser treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Before LTP, the mean IOP\u2009\u00b1\u2009standard deviation in all 152 study\u2010eyes of 122 multi\u2010treated patients was 14.0\u2009\u00b1\u20093.5\u2009mmHg. Three eyes of three deceased patients were lost to follow\u2010up during the 60\u2009months. After exclusion of eyes that received increased therapy during follow\u2010up, the IOP was significantly reduced at all visits up to 48\u2009months in eyes with pre\u2010LTP IOP \u226515\u2009mmHg; 2.6\u2009\u00b1\u20093.1\u2009mmHg at 1\u2009month and 1.7\u2009\u00b1\u20092.8\u2009mmHg at 48\u2009months, <jats:italic>n<\/jats:italic>\u2009=\u200956 and 48, respectively. No significant IOP reduction was seen in eyes with pre\u2010LTP IOP &lt;15\u2009mmHg. Seven eyes, i.e., &lt;13%, with pre\u2010LTP IOP \u226515\u2009mmHg at baseline had required increased IOP\u2010lowering therapy at 48\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LTP performed in multi\u2010treated patients may provide a useful IOP reduction that is maintained over several years. This was true on a group level when the initial IOP was \u226515\u2009mmHg, but if the pre\u2010laser IOP was lower than that, chances of LTP success were small.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15718","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T09:57:13Z","timestamp":1686131833000},"page":"179-185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Long\u2010term follow\u2010up of laser trabeculoplasty in multi\u2010treated glaucoma patients"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4102-2455","authenticated-orcid":false,"given":"Erika","family":"Rasmuson","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Ophthalmology Ume\u00e5 University  Ume\u00e5 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