{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:49:32Z","timestamp":1792234172752,"version":"4.4.0"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T00:00:00Z","timestamp":1687478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The purpose of this study was to investigate the uncertainty in the formula predicted refractive outcome REFU after cataract surgery resulting from measurement uncertainties in modern optical biometers using literature data for within\u2010subject standard deviation <jats:italic>S<\/jats:italic><jats:sub>w<\/jats:sub>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This Monte\u2013Carlo simulation study used a large dataset containing 16\u2009667 preoperative IOLMaster 700 biometric measurements. Based on literature <jats:italic>S<\/jats:italic><jats:sub>w<\/jats:sub> values, REFU was derived for both the Haigis and Castrop formulae using error propagation strategies. Using the Hoya Vivinex lens (IOL) as an example, REFU was calculated both with (WLT) and without (WoLT) consideration of IOL power labelling tolerances.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>WoLT the median REFU was 0.10\/0.12 dpt for the Haigis\/Castrop formula, and WLT it was 0.13\/0.15 dpt. WoLT REFU increased systematically for short eyes (or high power IOLs), and WLT this effect was even more pronounced because of increased labelling tolerances. WoLT the uncertainty in the measurement of the corneal front surface radius showed the largest contribution to REFU, especially in long eyes (and low power IOLs). WLT the IOL power uncertainty dominated in short eyes (or high power IOLs) and the uncertainty of the corneal front surface in long eyes (or low power IOLs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared with published data on the formula prediction error of refractive outcome after cataract surgery, the uncertainty of biometric measures seems to contribute with \u2153 to \u00bd to the entire standard deviation. REFU systematically increases with IOL power and decreases with axial length.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15726","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T23:57:08Z","timestamp":1687651028000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Impact of uncertainties in biometric parameters on intraocular lens power formula predicted refraction using a <scp>Monte\u2010Carlo<\/scp> simulation"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9175-6177","authenticated-orcid":false,"given":"Achim","family":"Langenbucher","sequence":"first","affiliation":[{"name":"Department of Experimental Ophthalmology Saarland University  Homburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Augen\u2010 und Laserklinik Castrop\u2010Rauxel  Castrop\u2010Rauxel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Cayless","sequence":"additional","affiliation":[{"name":"School of Physical Sciences The Open University  Milton Keynes UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8691-5276","authenticated-orcid":false,"given":"Matthias","family":"Bolz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Johannes Kepler University Linz  Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4145-2559","authenticated-orcid":false,"given":"Jascha","family":"Wendelstein","sequence":"additional","affiliation":[{"name":"Department of Experimental Ophthalmology Saarland University  Homburg Germany"},{"name":"Department of Ophthalmology Johannes Kepler University Linz  Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8019-1481","authenticated-orcid":false,"given":"N\u00f3ra","family":"Szentm\u00e1ry","sequence":"additional","affiliation":[{"name":"Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Aniridia Research Saarland University  Homburg Germany"},{"name":"Department of Ophthalmology Semmelweis\u2010University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0268856"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2018.1458881"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000552"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417\u2010022\u201005579\u20109"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417\u2010016\u20103555\u2010z"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.jcrs.0000000000000633"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.jcrs.0000000000001023"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10792\u2010016\u20100380\u20107"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004170000188"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X\u201020200729\u201003"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X\u201020190109\u201001"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol\u20102016\u2010308352"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2015.07.039"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14902"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0252102"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417\u2010021\u201005287\u2010w"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1364\/josaa.14.001684"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2018.10.033"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10742\u2010015\u20100137\u20101"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/17434440.2019.1557517"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0886\u20103350(96)80204\u20105"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.10.031"},{"key":"e_1_2_7_24_1","unstructured":"Ophthalmic Implants \u2013 Intraocular Lenses. 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