{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T11:46:26Z","timestamp":1788608786585,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T00:00:00Z","timestamp":1687219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>A comparison of the safety and efficacy of the MicroShunt versus trabeculectomy in the early postoperative period, with a particular focus on hypotony.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this registry study, we evaluated 200 eyes of 200 glaucoma patients who underwent filtration surgery at Oslo University Hospital between 2017 and 2021. Of these patients, 100 had a Preserflo MicroShunt (Santen) implantation and 100 had a trabeculectomy procedure. The patients were examined per standard hospital protocol after filtration surgery. Data were extracted from the 4\u2010 and 8\u2010week visits. We defined hypotony as intraocular pressure (IOP)\u2009&lt;\u20096\u2009mmHg.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean preoperative IOP was 20.6\u2009\u00b1\u20097.1\u2009mmHg in the MicroShunt group and 21.6\u2009\u00b1\u20097.1\u2009mmHg in the trabeculectomy group, and the patients used a mean of 3.0\u2009\u00b1\u20090.9 and 3.1\u2009\u00b1\u20090.9 glaucoma medications, respectively. After 8\u2009weeks, IOP was reduced to 10.4\u2009\u00b1\u20095.4\u2009mmHg and 11.3\u2009\u00b1\u20094.6\u2009mmHg, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.23). During the early postoperative period, hypotony was registered in 63% of the MicroShunt patients and in 21% of the patients in the trabeculectomy group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001); and 11% and 1%, respectively, of the patients developed choroidal detachments (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.003). One patient in the MicroShunt group required reoperation due to hypotony.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this registry study, we found that the Preserflo MicroShunt and trabeculectomy had equally satisfactory IOP\u2010lowering effects during the early postoperative period. In this same period, a high number of patients in the MicroShunt group developed hypotony.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15727","type":"journal-article","created":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T05:54:42Z","timestamp":1687326882000},"page":"186-191","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Hypotony in the early postoperative period after MicroShunt implantation versus trabeculectomy: A registry study"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0636-5591","authenticated-orcid":false,"given":"Anders Djupesland","family":"B\u00f8hler","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Oslo University Hospital  Oslo Norway"},{"name":"Institute of Clinical Medicine University of Oslo  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valgerdur 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