{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T23:43:58Z","timestamp":1771458238412,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T00:00:00Z","timestamp":1694649600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100013511","name":"Silm\u00e4s\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013511","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the long\u2010term symptom resolution and use of resources of performing endoscopic dacryocystorhinostomy (enDCR) in acute or delayed phase in patients with acute dacryocystitis (AD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective, randomised controlled trial was conducted in Helsinki University tertiary Eye and Ear, Nose and Throat (ENT) Hospitals between September 2013 and January 2019. Fifty patients aged 18 and above presenting with AD in the emergency care were randomised into acute and delayed enDCR surgery groups, performed in 1\u2009week or 4\u2009months from the diagnosis of AD. The follow\u2010up time was 18\u2009months. Outcome measures were subjective epiphora, lacrimal symptoms and visual analogue scale (VAS) pain scores, the number of hospitalised and unhealthy days, use of medication and openness in lacrimal syringing and dye test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>EnDCR was performed on 24 patients in the acute and 19 in the delayed group. There were no significant differences between the groups in follow\u2010up lacrimal symptoms, syringing test, dye test or use of resources. At the 18\u2009months' follow\u2010up, 21\/23 (91.3%) in the acute group and 12\/13 (92.3%) in the delayed group had no disturbing lacrimal symptoms. When reoperations and dropouts are considered, beneficial outcome was 22\/24 (91.7%) in the acute and 12\/16 (75%) (<jats:italic>p<\/jats:italic>\u2009=\u20090.195) in the delayed group. The acute group had significantly fewer pain medication days than the delayed group, 3 versus 10.5 (<jats:italic>p<\/jats:italic>\u2009=\u20090.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Acute enDCR is associated with fewer pain medication days and equal resolution of lacrimal symptoms and use of resources.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.15752","type":"journal-article","created":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T17:19:23Z","timestamp":1694711963000},"page":"441-447","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Acute versus late endoscopic dacryocystorhinostomy in treatment of acute dacryocystitis: A prospective randomised trial with an 18\u2010month follow\u2010up"],"prefix":"10.1111","volume":"102","author":[{"given":"Markus","family":"Lilja","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9983-6104","authenticated-orcid":false,"given":"Tiina","family":"Leivo","sequence":"additional","affiliation":[{"name":"Medical Faculty University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marita","family":"Uusitalo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seija","family":"Vento","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery Helsinki University Hospital and University of Helsinki  Helsinki 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Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2014-305510"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25380"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aanat.2019.07.009"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28528"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40123-022-00544-5"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/jovr.jovr_264_15"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002341-200105000-00006"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2017.4798"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814527236"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/01676830.2010.535952"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/01676830902925529"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-012-0507-8"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-019-0734-2"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10102161"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.09.041"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29693"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.18240\/ijo.2021.06.08"}],"container-title":["Acta 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