{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:06:47Z","timestamp":1789704407579,"version":"4.0.1"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T00:00:00Z","timestamp":1705104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To examine complications, visual outcomes, photic patient\u2010reported symptoms, corneal morphology, IOL tilt, and intraocular pressure after implantation of an intraocular lens (IOL) and iris prosthesis (IP) following iridocyclectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with previous iridocyclectomy treated with an IOL and IP at the Copenhagen University Hospital Rigshospitalet between 2007 and 2018 were included in this national retrospective non\u2010comparative case series. The assessment encompassed BCVA, PRO questionnaire, corneal topography, and anterior segment OCT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>45 patients were included. Eight of 45 patients were previously treated with ruthenium\u2010106 brachytherapy in conjunction with iridocyclectomy. Six of 45 patients developed endothelial dysfunction four of whom had received ruthenium\u2010106 brachytherapy. Five of 45 patients had subluxation of the IOL\/IP complex due to incomplete zonula apparatus. BCVA improved for all patients after lens surgery. 26 patients participated in the invited follow\u2010up examination. 19 of 26 (73%) reported none or mild photic symptoms after IP instalment. Five (19%) reported ongoing severe photic symptoms. The corneal astigmatism significantly increased after iridocyclectomy but did not change after lens surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Implantation of an IOL and IP is a safe procedure, alleviating photic symptoms in most patients. It comes with higher risk of complications due to a more demanding procedure and larger surgical traumas from previous treatments. Ruthenium\u2010106 brachytherapy increases the complication risk. Corneal astigmatism is induced by iridocyclectomy but does not change after lens surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.16610","type":"journal-article","created":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T14:38:30Z","timestamp":1705156710000},"page":"581-589","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcome of combined cataract surgery and iris prosthesis implantation in iris melanoma patients previously treated with iridocyclectomy: A national retrospective non\u2010comparative case series"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8007-8611","authenticated-orcid":false,"given":"Kristoffer","family":"Nissen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon Persson","family":"Skibsted","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6381-8465","authenticated-orcid":false,"given":"Mette Marie","family":"Bagger","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasmus","family":"Ejstrup","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2517-7270","authenticated-orcid":false,"given":"Carsten","family":"Faber","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Riise","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5906-7670","authenticated-orcid":false,"given":"Steffen","family":"Heegaard","sequence":"additional","affiliation":[{"name":"Department of Pathology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1054-1460","authenticated-orcid":false,"given":"Jens Folke","family":"Kiilgaard","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,13]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"23","article-title":"Melanoma of the iris: report of 72 cases treated surgically","volume":"6","author":"Arentsen J.J.","year":"1975","journal-title":"Ophthalmic Surgery"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.03.047"},{"key":"e_1_2_8_4_1","first-page":"848","article-title":"Primary iris melanoma: diagnostic features and outcome of conservative surgical treatment. 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