{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T19:18:44Z","timestamp":1785439124988,"version":"3.56.0"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To determine vision\u2010related quality of life (VR\u2010QoL) and functional and structural parameters associated with VR\u2010QoL in patients with glaucoma before and 12\u2009months after trabeculectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010eight patients undergoing trabeculectomy were included. Participants completed the 25\u2010item National Eye Institute Visual Function Questionnaire (VFQ\u201025) prior to and 12\u2009months after trabeculectomy. Functional (visual acuity and visual fields) and structural (ganglion cell layer volume) parameters were evaluated for their association with VR\u2010QoL using multiple linear regression of VFQ\u201025 subscale scores. Intraocular pressure and the number of glaucoma medications were also included in the analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The VFQ\u201025 composite score did not change after trabeculectomy (before: 74.9; 12\u2009months: 74.0; <jats:italic>p<\/jats:italic>\u2009=\u20090.512). The subscale <jats:italic>mental health<\/jats:italic> had a significantly higher score 12\u2009months after trabeculectomy (before: 65.6; 12\u2009months: 71.4; <jats:italic>p<\/jats:italic>\u2009=\u20090.017). The VFQ\u201025 scores for <jats:italic>general health<\/jats:italic> (before: 68.5; 12\u2009months: 62.5; <jats:italic>p<\/jats:italic>\u2009=\u20090.009) and <jats:italic>role difficulties<\/jats:italic> (before: 78.9; 12\u2009months: 53.7; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) were significantly lower 12\u2009months after trabeculectomy. No functional or structural parameters were associated with VFQ\u201025 composite score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Overall, VR\u2010QoL in glaucoma patients was similar before and after trabeculectomy, reflecting the procedure's stabilizing effect on both objective and subjective visual function. The absence of correlations between VR\u2010QoL and clinical parameters emphasizes the multifaceted nature of VR\u2010QoL and highlights the limitations of depending solely on objective clinical metrics to evaluate patients' subjective experiences. Using both objective measures and VR\u2010QoL, clinicians can better understand the challenges patients face due to glaucoma and trabeculectomy, potentially leading to better solutions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.16697","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T11:09:42Z","timestamp":1713956982000},"page":"779-789","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Vision\u2010related quality of life in patients with glaucoma before and after trabeculectomy"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9485-3033","authenticated-orcid":false,"given":"Mathilde M.","family":"von Arenstorff","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Copenhagen University Hospital\u2014Rigshospitalet Copenhagen  Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afrouz","family":"Ahmadzadeh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Copenhagen University Hospital\u2014Rigshospitalet Copenhagen  Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo Simmendefeldt","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Physics Technical University of Denmark  Kongens Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9375-1510","authenticated-orcid":false,"given":"Line","family":"Kessel","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Copenhagen University Hospital\u2014Rigshospitalet Copenhagen  Glostrup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8249-5104","authenticated-orcid":false,"given":"Daniella","family":"Bach\u2010Holm","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Copenhagen University Hospital\u2014Rigshospitalet Copenhagen  Glostrup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11247365"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40123-022-00636-2"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1586\/erp.11.59"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0013164414534258"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1543-5946(03)90003-1"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2017.1396"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(20)30489-7"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-013-0487-5"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.4908"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200004000-00010"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2020.01.030"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2021-egsguidelines"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.122.4.532"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2018.07.011"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001889"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.5319"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-017-0466-7"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(01)00874-0"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2018.0012"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n1014"},{"key":"e_1_2_7_22_1","first-page":"887","article-title":"Glaucoma is second leading cause of blindness globally","volume":"82","author":"Kingman S.","year":"2004","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2017.01.019"},{"key":"e_1_2_7_24_1","volume-title":"An introduction to mathematical statistics and its applications","author":"Larsen R.J.","year":"2012"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-09832-3"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.14028"},{"key":"e_1_2_7_27_1","unstructured":"Mangione C.M.(2000)Visual Function Questionnaire 25 | National Eye Institute. 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