{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:42:23Z","timestamp":1778546543526,"version":"3.51.4"},"reference-count":44,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T00:00:00Z","timestamp":1714348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>It is well established that children born very preterm are at increased risk for ocular abnormalities including altered foveal morphology. However, little is known about how children born moderate\u2010to\u2010late preterm (MLP), gestational age 32\u2009+\u20090\u201336\u2009+\u20096\u2009weeks, are affected later in life. This study investigates foveal avascular zone (FAZ) area, vascular density (VD), central foveal thickness (CFT) and ganglion cell layer thickness (GCL++) of adolescents born MLP without history of retinopathy of prematurity and compare the results with full\u2010term controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a prospective population\u2010based cohort study, 50 adolescents (26 girls; mean age 16.5\u2009years) born MLP were examined with optical coherence tomography (OCT) and OCT angiography (OCT\u2010A). FAZ and VD were obtained from OCT\u2010A scans and adjusted for ocular magnification. CFT and GCL++ were obtained from the OCT scans. The results from the MLP individuals were compared with the results from 49 healthy full\u2010term controls (29 girls; mean age 16.7\u2009years).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results showed statistically significant differences in FAZ area (0.22 vs 0.28\u2009mm<jats:sup>2<\/jats:sup>; <jats:italic>p<\/jats:italic>\u2009=\u20090.0032) and CFT (198.1 vs 187.1\u2009\u03bcm; <jats:italic>p<\/jats:italic>\u2009=\u20090.0010) between the MLP group and controls. Strong correlations between FAZ area and CFT (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.773, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) and GCL++ (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.924, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) were found in the MLP group. There were no differences in VD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results show that adolescents born MLP have a smaller FAZ area and an increased CFT compared with full\u2010term controls. These results indicate that adolescents born MLP have similar parafoveal changes as children born extreme or very preterm.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.16702","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T13:49:40Z","timestamp":1714398580000},"page":"797-804","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Foveal thickness and vascular variables in adolescents born moderate\u2010to\u2010late preterm"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7736-3277","authenticated-orcid":false,"given":"Titus","family":"Ovik","sequence":"first","affiliation":[{"name":"Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy University of Gothenburg  Gothenburg 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