{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T02:46:24Z","timestamp":1788921984042,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess associations between atrial fibrillation\/atrial flutter (AF) and ocular parameters and diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The population\u2010based Ural Eye and Medical Study (UEMS) and the Ural Very Old Study (UVOS) included 4894 individuals (age: 40+ years) and 835 individuals (age: 85+ years), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the UEMS, AF prevalence (80\/4894; 1.6%; 95% CI: 1.3, 2.0) increased from 1\/1029 (0.1%) in the age group of 40 to &lt;50\u2009years to 29\/619 (4.7%) and 12\/159 (7.5%) in the age groups of 70 to &lt;80\u2009years and 80+ years, respectively. Higher AF prevalence correlated with older age (OR: 1.08; 95% CI: 1.04, 1.12; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), urban region of habitation (OR: 1.08; 95% CI: 1.04, 1.12; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), higher prevalence of cardiovascular disease\/stroke (OR: 2.50; 95% CI: 1.32, 4.72; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and lower prevalence of neck pain (OR: 0.35; 95% CI: 0.14, 0.85; <jats:italic>p<\/jats:italic>\u2009=\u20090.02), higher serum concentration of bilirubin (OR: 1.03; 95% CI: 1.02, 1.05; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and lower prothrombin index (OR: 0.96; 95% CI: 0.93, 0.99; <jats:italic>p<\/jats:italic>\u2009=\u20090.003), higher stage of arterial hypertension (OR: 1.52; 95% CI: 1.01, 2.28; <jats:italic>p<\/jats:italic>\u2009=\u20090.04) and higher ankle\u2010brachial index (OR: 22.1; 95% CI: 4.45, 1.10; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). In that model, AF prevalence was not associated with ocular parameters such as intraocular pressure (<jats:italic>p<\/jats:italic>\u2009=\u20090.52), retinal nerve fibre layer thickness (<jats:italic>p<\/jats:italic>\u2009=\u20090.70), refractive error (<jats:italic>p<\/jats:italic>\u2009=\u20090.13), axial length (<jats:italic>p<\/jats:italic>\u2009=\u20090.14), nuclear cataract degree (<jats:italic>p<\/jats:italic>\u2009=\u20090.50) and prevalence (<jats:italic>p<\/jats:italic>\u2009=\u20090.40), cortical cataract degree (<jats:italic>p<\/jats:italic>\u2009=\u20090.43) and presence (<jats:italic>p<\/jats:italic>\u2009=\u20090.17), lens pseudoexfoliation (<jats:italic>p<\/jats:italic>\u2009=\u20090.58), status after cataract surgery (<jats:italic>p<\/jats:italic>\u2009=\u20090.38), age\u2010related macular degeneration prevalence (<jats:italic>p<\/jats:italic>\u2009=\u20090.63), open\u2010angle glaucoma presence (<jats:italic>p<\/jats:italic>\u2009=\u20090.90) and stage (<jats:italic>p<\/jats:italic>\u2009=\u20090.55), angle\u2010closure glaucoma prevalence (<jats:italic>p<\/jats:italic>\u2009=\u20090.99) and stage (<jats:italic>p<\/jats:italic>\u2009=\u20090.99), diabetic retinopathy prevalence presence (<jats:italic>p<\/jats:italic>\u2009=\u20090.37) and stage (<jats:italic>p<\/jats:italic>\u2009=\u20090.32), and myopic macular degeneration (<jats:italic>p<\/jats:italic>\u2009=\u20090.98). In the UVOS, similar results were obtained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In these multi\u2010ethnic populations from Russia, AF prevalence was not associated with any major ocular disease and may not play a major role in the pathogenesis of these disorders.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.16726","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T09:28:36Z","timestamp":1717234116000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Atrial fibrillation and flutter and ocular diseases. The Ural eye and medical study and the Ural very old study"],"prefix":"10.1111","volume":"102","author":[{"given":"Mukharram M.","family":"Bikbov","sequence":"first","affiliation":[{"name":"Ufa Eye Research Institute  Ufa Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyulli M.","family":"Kazakbaeva","sequence":"additional","affiliation":[{"name":"Ufa Eye Research Institute  Ufa Russia"},{"name":"Ufa Eye Institute  Ufa Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellina M.","family":"Rakhimova","sequence":"additional","affiliation":[{"name":"Ufa Eye Research Institute  Ufa Russia"},{"name":"Ufa Eye Institute  Ufa Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songhomitra","family":"Panda\u2010Jonas","sequence":"additional","affiliation":[{"name":"Privatpraxis Prof Jonas Und Dr Panda\u2010Jonas  Heidelberg Germany"},{"name":"Department of Ophthalmology Heidelberg University  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albina A.","family":"Fakhretdinova","sequence":"additional","affiliation":[{"name":"Ufa Eye Research Institute  Ufa Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azaliia M.","family":"Tuliakova","sequence":"additional","affiliation":[{"name":"Ufa Eye Research Institute  Ufa Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iulia A.","family":"Rusakova","sequence":"additional","affiliation":[{"name":"Ufa Eye Research Institute  Ufa Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2972-5227","authenticated-orcid":false,"given":"Jost B.","family":"Jonas","sequence":"additional","affiliation":[{"name":"Institut Fran\u00e7ais de Myopie H\u00f4pital Fondation Rothschild  Paris France"},{"name":"Singapore Eye Research Institute Singapore National Eye Center  Singapore City Singapore"},{"name":"New York Eye and Ear Infirmary of Mount Sinai Icahn School of Medicine at Mount Sinai  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.0567"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-77344-z"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.21138"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2010.11.012"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.005119"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gheart.2014.01.004"},{"key":"e_1_2_5_8_1","unstructured":"Federal State Statistic Service. 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