{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:39:34Z","timestamp":1789141174351,"version":"build-2803163510"},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T00:00:00Z","timestamp":1718064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Central serous chorioretinopathy (CSC) is a frequently occurring chorioretinal disease, that is commonly associated with subretinal fluid accumulation in a generally young population. Even though choroidal abnormalities have been found to be of importance, the exact pathogenesis of CSC is still being learned. The origin of pigment epithelial detachments, seen in many CSC patients, is also unclear. Based on the follow\u2010up of a CSC patient for more than 5\u2009years, we hypothesize that intraocular pressure and, by extension, the pressure gradient across the Bruch's membrane, may be one factor in the pathogenesis of pigment epithelial detachments in CSC, which might very well have implications for the occurrence of and possible ways to prevent subretinal fluid in CSC.<\/jats:p>","DOI":"10.1111\/aos.16730","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T08:05:40Z","timestamp":1718093140000},"page":"843-848","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A possible association between intraocular pressure changes and pigment epithelial detachment in central serous chorioretinopathy"],"prefix":"10.1111","volume":"102","author":[{"given":"Chandrakumar","family":"Balaratnasingam","sequence":"first","affiliation":[{"name":"Centre for Ophthalmology and Visual Science University of Western Australia  Perth Western Australia Australia"},{"name":"Lions Eye Institute  Nedlands Western Australia Australia"},{"name":"Retina Service, Department of Ophthalmology Sir Charles Gairdner Hospital  Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine A.","family":"Curcio","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences University of Alabama at Birmingham, Heersink School of Medicine  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William H.","family":"Morgan","sequence":"additional","affiliation":[{"name":"Centre for Ophthalmology and Visual Science University of Western Australia  Perth Western Australia Australia"},{"name":"Lions Eye Institute  Nedlands Western Australia Australia"},{"name":"Glaucoma Service, Department of Ophthalmology Royal Perth Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6351-7942","authenticated-orcid":false,"given":"Elon H. 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