{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T17:20:11Z","timestamp":1763572811637,"version":"3.40.5"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:00:00Z","timestamp":1730937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010816","name":"Stiftelsen f\u00f6r Synskadade i f.d. Malm\u00f6hus l\u00e4n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010816","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To analyse graft detachment rates after Descemet stripping automated endothelial keratoplasty (DSAEK) using surgeon\u2010cut grafts and pre\u2010cut grafts transported in different mediums.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study of graft detachment rates including 265 surgeries (240 patients) performed between 2019 and 2023. The DSAEK grafts were either surgeon\u2010cut (<jats:italic>n<\/jats:italic>\u2009=\u2009135) or pre\u2010cut and transported in a dextran\u2010containing medium (<jats:italic>n<\/jats:italic>\u2009=\u200982) or in a dextran\u2010free medium (<jats:italic>n<\/jats:italic>\u2009=\u200948). All surgeries were performed by a single surgeon (I.G.). The surgeries were categorised according to whether the recipients' eyes had, or did not have, factors associated with an increased risk of graft detachment. Detachment rates were compared for all patients receiving the different kinds of graft, and only for those without risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significantly higher detachment rate was found among patients receiving pre\u2010cut grafts transported in a dextran\u2010containing medium (32.9%), compared to surgeon\u2010cut grafts (14.1%, <jats:italic>p<\/jats:italic>\u2009=\u20090.002), and pre\u2010cut grafts transported in a dextran\u2010free medium (6.3%, <jats:italic>p<\/jats:italic>\u2009=\u20090.002) for all recipients (those with and without risk factors for graft detachment). When analysing recipients without risk factors for graft detachment, the detachment rate was still significantly higher with pre\u2010cut tissue transported in a dextran\u2010containing medium (26.9%), compared to surgeon\u2010cut tissue (8.3%, <jats:italic>p<\/jats:italic>\u2009=\u20090.002) and pre\u2010cut tissue transported in a dextran\u2010free medium (3.6%, <jats:italic>p<\/jats:italic>\u2009=\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of pre\u2010cut DSAEK tissue transported in a dextran\u2010containing medium significantly increases the risk of graft detachment requiring re\u2010bubbling.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.16791","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T14:25:01Z","timestamp":1730989501000},"page":"281-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Graft detachment rates in surgeon\u2010cut and pre\u2010cut tissue for <scp>DSAEK<\/scp> transported in different mediums"],"prefix":"10.1111","volume":"103","author":[{"given":"Thorbj\u00f6rg","family":"Olafsdottir","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Department of Clinical Sciences, Sk\u00e5ne University Hospital Lund University  Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faisal","family":"Hootak","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Centralsjukhuset Kristianstad  Kristianstad Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carina","family":"Forslund","sequence":"additional","affiliation":[{"name":"Tissue Bank Sk\u00e5ne University Hospital  Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eydis","family":"Olafsdottir","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Department of Clinical Sciences, Sk\u00e5ne University 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