{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:45:27Z","timestamp":1789015527240,"version":"build-2803163510"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the intraocular pressure (IOP) lowering effect and success rate of Paul glaucoma implant (PGI) in refractory glaucoma after changing practice pattern from Ahmed and Baerveldt tubes to PGI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective observational study of the first 50 consecutive PGI surgeries at a single Danish tertiary centre from January 2022 to October 2023. Primary endpoints were IOP and success rates after 12\u2009months. Secondary endpoints were the use of IOP\u2010lowering medications and complications. All cases had a risk of failure for traditional glaucoma surgery (neovascular glaucoma, oil\u2010filled eye or uveitis).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Preoperative IOP was 29.9\u2009\u00b1\u20098.6\u2009mmHg and the mean number of topical IOP\u2010lowering medications used was 3.4\u2009\u00b1\u20090.76 with 14 cases of systemic acetazolamide. Twelve months after surgery IOP was reduced to 11.4\u2009\u00b1\u20093.1\u2009mmHg and complete success rate with (a) IOP\u226421\u2009mmHg was achieved in 43%, (b) IOP\u226418\u2009mmHg in 43%, (c) IOP\u226415\u2009mmHg in 41% and (d) IOP\u226412\u2009mmHg in 33%. Qualified success rate (on topical glaucoma medications) was achieved in (a) 96%, (b) 94%, (c) 86% and (d) 71% of the cases.<\/jats:p>\n                    <jats:p>The number of topical IOP\u2010lowering medications was 0.9\u2009\u00b1\u20090.9 after surgery and 47% were medication free. Early (&lt;3\u2009months) and late (&gt;3\u2009months) complications were observed in 22% and 16% of patients respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study indicates that PGI provides a good IOP\u2010lowering effect after 12\u2009months in a population with risk factors for failure for traditional glaucoma surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.17443","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T07:18:12Z","timestamp":1737703092000},"page":"461-468","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["One tube for all: 1\u2010year outcomes after transition to Paul glaucoma implant at a tertiary centre"],"prefix":"10.1111","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8463-8359","authenticated-orcid":false,"given":"Anne","family":"Studsgaard","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stine Elkj\u00e6r","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8327-6461","authenticated-orcid":false,"given":"Niklas","family":"Telinius","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2023-egsguidelines"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.07.016"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.05.004"},{"key":"e_1_2_6_5_1","article-title":"Treatment outcomes in the tube versus trabeculectomy study after one year of follow\u2010up","volume":"143","author":"Gedde S.","year":"2007","journal-title":"American Journal of Ophthalmology"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2022.07.003"},{"key":"e_1_2_6_7_1","article-title":"Treatment outcomes in the tube versus trabeculectomy (TVT) study after five years of follow\u2010up","volume":"153","author":"Gedde S.J.","year":"2012","journal-title":"American Journal of Ophthalmology"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001969"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogla.2020.05.001"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2023.09.023"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-021-01737-1"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.14235"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.17443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T03:10:53Z","timestamp":1748661053000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.17443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,24]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/aos.17443"],"URL":"https:\/\/doi.org\/10.1111\/aos.17443","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,24]]},"assertion":[{"value":"2024-10-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}