{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T23:08:15Z","timestamp":1787699295872,"version":"build-2784847793"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100020039","name":"Ole Kirk's Fond","doi-asserted-by":"publisher","award":["21\u20105\u20100289"],"award-info":[{"award-number":["21\u20105\u20100289"]}],"id":[{"id":"10.13039\/100020039","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The agreement between children with strabismus and their parents on the health\u2010related quality of life (HRQOL) of the child is unknown. Additionally, it is unknown if physical traits pre\u2010dispose to a better outcome in HRQOL after strabismus surgery in children. This study aims to aid strabismus surgeons in deciding which children will improve HRQOL following strabismus surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included 114 Danish children who underwent strabismus surgery for their strabismus and 29 controls without ophthalmologic manifestations. Each child and their parent answered questionnaires about the child's eye\u2010 and general health. We compared eye\u2010specific, psychosocial and physical scores in children pre\u2010 and post\u2010operatively with controls. We also investigated child\u2013parent (proxy) agreement and whether sex, age and strabismus type were associated with improvement in HRQOL after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Children with strabismus scored themselves lower on eye\u2010related HRQOL questions than their parents scored them (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). Children with strabismus had similar improvements in HRQOL after surgery independent of age, sex, use of glasses and type of strabismus. Children with strabismus scored lower across all questionnaires on HRQOL even after surgery compared to controls (eye specific,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001; PedsQL psychosocial\u2009=\u20090.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Strabismus surgery in children improved their quality of life regardless of sex, age, wearing glasses or strabismus type. The surgeon should be aware of potential discrepancies in perception of the HRQOL of the child, between the child and their parent when making their assessment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.17543","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T18:51:11Z","timestamp":1753728671000},"page":"82-88","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Health\u2010related quality of life of children with strabismus"],"prefix":"10.1111","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0243-8607","authenticated-orcid":false,"given":"Lena","family":"Boulakh","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet\u2010Glostrup  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas L.","family":"Isaksen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3088-4375","authenticated-orcid":false,"given":"Christina","family":"Ellervik","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health and Medical Science University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Laboratory Medicine, Harvard Medical School Boston Children's Hospital  Boston Massachusetts USA"},{"name":"Department of Clinical Biochemistry Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f8rgen K.","family":"Kanters","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences University of Copenhagen  Copenhagen Denmark"},{"name":"Center for Biosignal Research University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena Buch","family":"Hesgaard","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Sahlgrenska University Hospital  Gothenburg Sweden"},{"name":"Department of Neuroscience and Physiology Gothenburg University  Gothenburg Sweden"},{"name":"Copenhagen Eye and Strabismus Clinic  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisbeth","family":"Sandfeldt","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health and Medical Science University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Ophthalmology Zealand University Hospital  Roskilde 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