{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T17:00:37Z","timestamp":1786467637390,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In this study, we systematically review and synthesize the evidence on the association between central serous chorioretinopathy (CSC) and personality types, and quantify the relationship between Type A behaviour and CSC. We systematically searched 12 literature databases on 5 October 2025 for studies in which personality types were evaluated in patients with CSC. Data extraction and risk\u2010of\u2010bias assessment followed standardized protocols. Studies were reviewed qualitatively. Random\u2010effects meta\u2010analysis was performed for the association between Type A behaviour and CSC. Twelve studies of 2176 participants (949 patients with CSC, 1227 controls) were included. Across studies, patients with CSC exhibited personality profiles marked by time urgency, competitiveness, emotional tension and maladaptive affect regulation, including higher neuroticism\u2010anxiety, aggression\u2010hostility and alexithymia scores. A significant association was found between Type A behaviour and CSC (pooled OR 3.43; 95% CI 1.94\u20136.07;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.00002) in the four studies that evaluated this relationship. Sensitivity analysis confirmed robustness of the association. In conclusion, certain personality traits, particularly Type A behaviour, are associated with CSC. The relationship between personality and CSC appears biologically plausible given the role of stress\u2010related hypothalamic\u2013pituitary\u2013adrenal axis activation and elevated cortisol levels, both recognized in CSC pathophysiology. However, complex biopsychosocial interactions without a direct causal pathway may also be the case. Understanding psychological predispositions may contribute to a more comprehensive view of CSC risk and care. Further longitudinal and mechanistic studies are warranted.\n                  <\/jats:p>","DOI":"10.1111\/aos.70097","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T13:45:26Z","timestamp":1770817526000},"page":"638-648","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between central serous chorioretinopathy and personality types: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"104","author":[{"given":"Emil","family":"\u00d8rnberg","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Bruun","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8693-8256","authenticated-orcid":false,"given":"Younes","family":"Subhi","sequence":"additional","affiliation":[{"name":"Mental Health Centre Sct. Hans, Capital Region of Denmark  Roskilde Denmark"},{"name":"Department of Emergency Medicine Holb\u00e6k Hospital  Holb\u00e6k Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2382-1111","authenticated-orcid":false,"given":"Rodrigo","family":"Anguita","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital, NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lasse J.","family":"Cehofski","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0715-6369","authenticated-orcid":false,"given":"Lorenzo Ferro","family":"Desideri","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital University Hospital Bern, University of Bern  Bern Switzerland"},{"name":"Department for Bio Medical Research University of Bern  Bern Switzerland"},{"name":"Bern Photographic Reading Center, Inselspital University Hospital Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elon H. C.","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Leiden University Medical Centre  Leiden the Netherlands"},{"name":"Rotterdam Eye Hospital  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8610-7455","authenticated-orcid":false,"given":"Michael S.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Glostrup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver N.","family":"Klefter","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Glostrup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4304-9704","authenticated-orcid":false,"given":"Danson V.","family":"Muttuvelu","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0807-2650","authenticated-orcid":false,"given":"Line","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Cem","family":"Sabaner","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Bilecik Training and Research Hospital  Bilecik T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1488-4743","authenticated-orcid":false,"given":"Miklos","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet  Glostrup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Ophthalmology Semmelweis University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7130-4798","authenticated-orcid":false,"given":"M. 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