{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:46:23Z","timestamp":1782938783263,"version":"3.54.5"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To provide numerical quantitative measurements of blood flow velocity in the optic nerve head (ONH) and choroid and retinal vascular oxygen saturation in patients with central retinal artery occlusion (CRAO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twelve consecutive patients (12 eyes) underwent laser speckle flowgraphy (LSFG) and retinal oximetry measurements at presentation. The normal fellow eyes were evaluated and used as controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In eyes with CRAO, the ONH mean blur rate (MBR)\u2010vessel (25\u2009\u00b1\u200915\u2009AU), representing blood flow velocity in the large vessels originating from the central retinal artery, ONH MBR\u2010tissue (9\u2009\u00b1\u20094\u2009AU) and choroidal MBR (7\u2009\u00b1\u20093\u2009AU), representing blood flow velocity in the short posterior ciliary arteries, were significantly reduced compared with fellow eyes (48\u2009\u00b1\u200910\u2009AU; 15\u2009\u00b1\u20094\u2009AU; 9\u2009\u00b1\u20093\u2009AU, respectively) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.034, respectively). The eyes with CRAO had significantly reduced oxygen saturation in retinal arterioles (85\u2009\u00b1\u20096%) and arteriovenous oxygen saturation difference (35\u2009\u00b1\u200916%) compared with fellow eyes (105\u2009\u00b1\u200918%; 49\u2009\u00b1\u200914%, respectively) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.043, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LSFG blood flow and retinal oximetry measurements provide quantitative measurements of the ocular arterial circulation and retinal oxygen metabolism alterations in patients with CRAO.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.70167","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:29:46Z","timestamp":1782937786000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ocular blood flow and retinal oxygen saturation measurements in central retinal artery occlusion"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2226-8617","authenticated-orcid":false,"given":"Ahmed M.","family":"Abu El\u2010Asrar","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, College of Medicine King Saud University  Riyadh Saudi Arabia"},{"name":"Arab National Bank Research Chair in Ophthalmology, College of Medicine King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abeer A.","family":"Alhazzani","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman F.","family":"Albloushi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Alzubaidi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscilla W.","family":"Gikandi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Einar","family":"Stef\u00e1nsson","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Physiology University of Iceland  Reykjavik 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