{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T06:31:22Z","timestamp":1776839482742,"version":"3.51.2"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,9,17]],"date-time":"2012-09-17T00:00:00Z","timestamp":1347840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim:\u2002<\/jats:bold> To characterize the features of juvenile parotitis in a prospective setup and epidemiology.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> All children with parotitis admitted to Helsinki University Central Hospital 2005\u20132010 were recruited. Clinical characteristics, given treatment, outcome, blood leukocyte count, C\u2010reactive protein, serum amylase and trypsinogen, SPINK\u20101 genotype and mumps antibodies were recorded. To map the epidemiology, a questionnaire was sent to 1000 randomly selected 13\u2010year\u2010old children.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> The prospective study included 41 children (aged\u2003\u2264\u200317) with acute parotitis, all in good general condition. Serum amylase, but not trypsinogen, was elevated in majority of the cases (79%) and C\u2010reactive protein in 68%. Eleven (27%) children had an elevated blood leukocyte count. None had acute mumps. Most children recovered well, 51% being treated symptomatically only. Seven children were treated on ward. Seventeen (46%) children had recurrent symptoms. One child (2.4%) had SPINK P55S mutation. According to the epidemiological questionnaire, 1.1% of the respondents (8\/728, response rate 73%) reported a verified episode(s) of parotitis.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Juvenile parotitis has a frequency close to 1%. In the majority, the general condition is good during the episode. Serum amylase serves as an additional marker for the disease. Parotitis has a tendency to recur in almost half of the cases.<\/jats:p>","DOI":"10.1111\/apa.12004","type":"journal-article","created":{"date-parts":[[2012,8,27]],"date-time":"2012-08-27T19:14:49Z","timestamp":1346094889000},"page":"177-181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["The clinical picture of juvenile parotitis in a prospective setup"],"prefix":"10.1111","volume":"102","author":[{"given":"Riitta","family":"Saarinen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaija\u2010Leena","family":"Kolho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irja","family":"Davidkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Pitk\u00e4ranta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,17]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.20.2643"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/427338"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31823247d4"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(94)01120-M"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200301000-00006"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000702"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/08035250505100399"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.5.687"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365520510011560"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.08.001"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.10417"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.1.9"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.02.011"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.06.012"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2005.00773.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2006.00804.x"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.7.715"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.09.027"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2011.03.013"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2005.10.008"},{"key":"e_1_2_7_22_2","first-page":"199","article-title":"Salivary factors in children with recurrent parotitis. part 2: protein, albumin, amylase, IgA, lactoferrin lysozyme and kallikrein concentrations","volume":"20","author":"Ericson S","year":"1996","journal-title":"Swed Dent J"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365520310000357"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(95)00064-8"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000246196.35413.35"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapa.12004","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.12004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T12:46:13Z","timestamp":1697373973000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.12004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,17]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1111\/apa.12004"],"URL":"https:\/\/doi.org\/10.1111\/apa.12004","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,17]]},"assertion":[{"value":"2012-09-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}