{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:58:25Z","timestamp":1791824305406,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,1,19]],"date-time":"2013-01-19T00:00:00Z","timestamp":1358553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The perfusion index (<jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>) and its dynamic change during respiration, and supressed the plethysmographic variability index (<jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>), are calculated from pulse oximetry, and these indexes were recently proposed for continuous and noninvasive assessment of peripheral perfusion in neonates. We aimed to assess the effect of patent ductus arteriosus (<jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>) on <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>, according to ductal <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>oppler flow pattern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010five neonates with median (Q25\u201075) gestational age (<jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>) and birthweight of 27 (25\u201328) weeks and 857 (750\u20131080) grams, respectively, were assessed prospectively using serial echocardiography and pulse oximetry during the first postnatal week.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Perfusion index increased from 0.70 (0.50\u20131.05) at day 1 to 1.50 (1.0\u20132.00) at day 7 (p\u00a0&lt;\u00a00.01) and was not influenced by ductal flow pattern. <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content> was 22 (18\u201327) and did not vary during the study period but differed according to ductal flow pattern, with lower values in the growing and pulsatile groups compared with the pulmonary hypertension (p\u00a0&lt;\u00a00.05), closing and closed groups (p\u00a0&lt;\u00a00.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ductal persistence and flow pattern did not affect <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content> but did affect <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content> in preterm neonates of less than 29\u00a0weeks of <jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>. Future studies are needed to establish the usefulness of <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content> in the early detection and management of <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content> in preterm neonates.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12130","type":"journal-article","created":{"date-parts":[[2012,12,13]],"date-time":"2012-12-13T17:03:45Z","timestamp":1355418225000},"page":"373-378","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Perfusion index and its dynamic changes in preterm neonates with patent ductus arteriosus"],"prefix":"10.1111","volume":"102","author":[{"given":"Magalie","family":"Vidal","sequence":"first","affiliation":[{"name":"Neonatology Department Arnaud de Villeneuve Hospital CHU Montpellier 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