{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T07:20:35Z","timestamp":1790493635798,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,3,6]],"date-time":"2013-03-06T00:00:00Z","timestamp":1362528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To study cord blood concentrations of adiponectin and leptin in children born by normal weight, overweight and obese mothers and to study these parameters in relation to a weight gain intervention programme for obese mothers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ten millilitre cord blood was collected and analysed for leptin and adiponectin concentrations in children with gestational age &gt;37\u00a0weeks born by 60 normal weight, 45 overweight and 145 obese mothers. 82 obese mothers took part in a weight gain intervention programme.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Concentrations of leptin and adiponectin were higher in cord blood from children of overweight and obese mothers compared with children of normal weight mothers (leptin: Md 13.2, 30, 3 and 90.2\u00a0ng\/mL respectively, p\u00a0&lt;\u00a00.001; adiponectin 35.9, 205.4, 213.8\u00a0ng\/L p\u00a0&lt;\u00a00.001). No differences were found between overweight and obese mothers.<\/jats:p><jats:p>The weight gain intervention programme for obese pregnant women had significant effects on the weight gain during pregnancy but had no effects on cord blood serum concentrations of leptin and adiponectin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cord blood leptin and adiponectin concentrations were higher in children born by overweight or obese women compared with children of normal weight mothers. A weight gain intervention programme for obese pregnant women did not affect these results. Intrauterine exposition to high concentrations of leptin and adiponectin may play a role in weight development later in life.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12202","type":"journal-article","created":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T17:46:08Z","timestamp":1360863968000},"page":"620-624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Leptin and adiponectin in cord blood from children of normal weight, overweight and obese mothers"],"prefix":"10.1111","volume":"102","author":[{"given":"Jan","family":"Brynhildsen","sequence":"first","affiliation":[{"name":"Division of Obstetrics and Gynecology Department of Clinical and Experimental Medicine Faculty of Health Sciences Link\u00f6ping University, Department of Obstetrics and Gynaecology in Link\u00f6ping, County Council of \u00d6sterg\u00f6tland Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunilla","family":"Sydsj\u00f6","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Department of Clinical and Experimental Medicine Faculty of Health Sciences Link\u00f6ping University, Department of Obstetrics and Gynaecology in Link\u00f6ping, County Council of \u00d6sterg\u00f6tland Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Blomberg","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Department of Clinical and Experimental Medicine Faculty of Health Sciences Link\u00f6ping University, Department of Obstetrics and Gynaecology in Link\u00f6ping, County Council of \u00d6sterg\u00f6tland Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ing\u2010Marie","family":"Claesson","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Department of Clinical and Experimental Medicine Faculty of Health Sciences Link\u00f6ping University, Department of Obstetrics and Gynaecology in Link\u00f6ping, County Council of \u00d6sterg\u00f6tland Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvar","family":"Theodorsson","sequence":"additional","affiliation":[{"name":"Division of Laboratory 1 Department of Clinical and Experimental Medicine Faculty of Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredrik","family":"Nystr\u00f6m","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine Department of Medical and Health Sciences Faculty of Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Sydsj\u00f6","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Department of Clinical and Experimental Medicine Faculty of Health Sciences Link\u00f6ping University, Department of Obstetrics and Gynaecology in Link\u00f6ping, County Council of \u00d6sterg\u00f6tland Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Josefsson","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Department of Clinical and Experimental Medicine Faculty of Health Sciences Link\u00f6ping University, Department of Obstetrics and Gynaecology in Link\u00f6ping, County Council of \u00d6sterg\u00f6tland Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102431\u20108\u20108"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00578-4"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000188387.88032.41"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000142713.53197.91"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.09.058"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00546.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000141442.59573.cd"},{"key":"e_1_2_10_9_1","volume-title":"Obesity, Preventing and Managing the Global Epidemic","author":"WHO","year":"1997"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2005.10.015"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000107291.46159.00"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2011.05.002"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.1.76"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/86.4.907"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1275521"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2010.12.005"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1808"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050801929869"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm.2002.195"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199803000-00005"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1999.00761.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2004.050"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2004.02041.x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01531.x"},{"key":"e_1_2_10_25_1","first-page":"680","article-title":"Maternal weight gain during pregnancy. Relation to prepregnancy weight","volume":"71","author":"Kanadys WM","year":"2000","journal-title":"Ginekol Pol"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-199112000-00002"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2010.03.004"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-0343"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2006.02736.x"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapa.12202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.12202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T07:17:28Z","timestamp":1697613448000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.12202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1111\/apa.12202"],"URL":"https:\/\/doi.org\/10.1111\/apa.12202","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,6]]},"assertion":[{"value":"2013-01-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-02-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-03-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}