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In keeping with extensive clinical use of this diuretic, the only side effect was a small hypokalaemia. A double\u2010blind clinical trial is warranted to test the efficacy of bumetanide in <jats:styled-content style=\"fixed-case\">FRX<\/jats:styled-content>.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> This single case report showed an improvement of the scores of each test used after 3\u00a0months of treatment. Double\u2010blind clinical trials are warranted to test the efficacy of bumetanide in <jats:styled-content style=\"fixed-case\">FRX<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/apa.12235","type":"journal-article","created":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T04:31:13Z","timestamp":1367901073000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Treating <scp>F<\/scp>ragile <scp>X<\/scp> syndrome with the diuretic bumetanide: a case report"],"prefix":"10.1111","volume":"102","author":[{"given":"Eric","family":"Lemonnier","sequence":"first","affiliation":[{"name":"Laboratory of Neurosciences de Brest University of Bretagne Occidentale Brest France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga\u00eblle","family":"Robin","sequence":"additional","affiliation":[{"name":"Child Psychiatry Service Centre de Ressources Autisme CHRU of Brest Brest 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