{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T15:56:40Z","timestamp":1785254200569,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,4,16]],"date-time":"2013-04-16T00:00:00Z","timestamp":1366070400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To screen for neurological and behavioural disorders in a paediatric cohort of patients with coeliac disease (<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>) in order to detect possible differences related to compliance with gluten\u2010free diet (<jats:styled-content style=\"fixed-case\">GFD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We recruited a cohort of 139 patients divided into three groups: A (40 patients with newly diagnosed <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>), B (54 patients with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> in remission after <jats:styled-content style=\"fixed-case\">GFD<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> (45 patients with potential <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>). Patients first underwent a screening neurological visit, detecting signs associated with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>, and then were evaluated with <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ediatric <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ymptom <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hecklist (<jats:styled-content style=\"fixed-case\">PSC<\/jats:styled-content>), a psychosocial screen for cognitive, emotional and behavioural problems.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the group <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> as compared to group <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>, there was a statistically significant decrease (p\u00a0&lt;\u00a00.05) in the incidence of chronic fatigue, headache and inattention. The same applied to patients compliant to <jats:styled-content style=\"fixed-case\">GFD<\/jats:styled-content> vs. non\u2010compliant. Potential coeliacs turning into overt <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> had a higher incidence of headache and inattention compared with potential coeliacs showing normal mucosa. The <jats:styled-content style=\"fixed-case\">PSC<\/jats:styled-content> mean score in group <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> was statistically higher than in group <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Gluten\u2010free diet had a positive impact on neuropsychiatric symptoms. We suggest the use of <jats:styled-content style=\"fixed-case\">PSC<\/jats:styled-content> in the routine follow\u2010up of coeliacs in order to allow an early detection of psychosocial problems.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12239","type":"journal-article","created":{"date-parts":[[2013,3,23]],"date-time":"2013-03-23T08:58:25Z","timestamp":1364029105000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The <scp>P<\/scp>ediatric <scp>S<\/scp>ymptom <scp>C<\/scp>hecklist as screening tool for neurological and psychosocial problems in a paediatric cohort of patients with coeliac disease"],"prefix":"10.1111","volume":"102","author":[{"given":"Gaetano","family":"Terrone","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Naples Federico II Naples 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