{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T06:07:46Z","timestamp":1744178866681},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,11,9]],"date-time":"2013-11-09T00:00:00Z","timestamp":1383955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To study the clinical impact of multiple viral respiratory infections compared to single infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Demographic data from 37 multiple infection periods in children &lt;5\u00a0years of age were compared to data from 193 episodes with single infections. Clinical data derived from patient records of the multiple infection episodes were further compared to data from 93 matched control episodes with single infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of patients with multiple viral findings was 12.7\u00a0months, compared to 5.7\u00a0months for those with single findings (p\u00a0&lt;\u00a00.01). Wheezing was the most common diagnosis in both groups, except among children who were only infected with the coronavirus. No differences were found regarding duration of hospitalisation, oxygen treatment or admittance to the intensive care unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children with multiple viral findings in their respiratory secretions were older than those with a single detected virus. Otherwise, no major differences in comorbidity, presentation or clinical outcome were observed between the two groups.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12440","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T01:26:12Z","timestamp":1381541172000},"page":"100-104","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Children with multiple viral respiratory infections are older than those with single viruses"],"prefix":"10.1111","volume":"103","author":[{"given":"Maria","family":"Rotz\u00e9n\u2010\u00d6stlund","sequence":"first","affiliation":[{"name":"Department of Clinical Microbiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Microbiology, Tumor and Cell Biology Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margareta","family":"Eriksson","sequence":"additional","affiliation":[{"name":"Astrid Lindgren Children\u2032s Hospital Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annika","family":"Tiveljung Lindell","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Microbiology, Tumor and Cell Biology Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Allander","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Microbiology, Tumor and Cell Biology Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benita","family":"Zweygberg Wirgart","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Microbiology, Tumor and Cell Biology Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Grillner","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Microbiology, Tumor and Cell Biology Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61051-9"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60206-1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2003.00056.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2008.04.002"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504666102"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2011.11.011"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/89098"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3038.2000.00076.x"},{"key":"e_1_2_8_10_1","first-page":"834","article-title":"Simultaneous infection with respiratory syncytial virus and other respiratory pathogens","volume":"142","author":"Tristram DA","year":"1988","journal-title":"Am J Dis Child"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21108"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31815b4935"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181694fb9"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000143648.04673.6c"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-3703"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31815922c8"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21368"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540410015295"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21271"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.10.4632-4635.2004"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1086\/426457"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000207395.80657.cf"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000183773.80217.12"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00030-07"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1086\/652405"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20588"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapa.12440","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.12440","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T22:27:01Z","timestamp":1696458421000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.12440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,9]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1111\/apa.12440"],"URL":"https:\/\/doi.org\/10.1111\/apa.12440","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,9]]},"assertion":[{"value":"2012-12-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-09-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-11-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}