{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T17:22:00Z","timestamp":1768929720642,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T00:00:00Z","timestamp":1387843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>There are a number of genetic and environmental factors that are associated with an increased risk of developing coeliac disease. Our aim was to determine whether socio\u2010economic deprivation increases or reduces the development of the disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study identified all children &lt;16 years old diagnosed with coeliac disease in the same tertiary paediatric centre between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 1995 and <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2011. Data, including age at diagnosis and postcode, were collected and linked with the quintile rank of the <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>elsh <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex of <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ultiple <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>eprivation score 2008, a measure of socio\u2010economic status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 232 patients and identified a graded association between the prevalence of coeliac disease and socio\u2010economic deprivation, which showed a higher rate in children living in more affluent areas. The largest difference was between the lowest deprivation level (rate\/1000\u00a0=\u00a01.16) and the highest deprivation level (rate\/1000\u00a0=\u00a00.49).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In our population, coeliac disease was more common in children in the higher socio\u2010economic groupings. The reasons for this are not clear, but perhaps both the \u2018hygiene hypothesis\u2019 and the health seeking behaviours of parents with high socio\u2010economic status are possible factors in the more frequent diagnosis of coeliac disease in this group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12494","type":"journal-article","created":{"date-parts":[[2013,11,5]],"date-time":"2013-11-05T04:38:49Z","timestamp":1383626329000},"page":"289-294","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Coeliac disease is more common in children with high socio\u2010economic status"],"prefix":"10.1111","volume":"103","author":[{"given":"LA","family":"Whyte","sequence":"first","affiliation":[{"name":"Department of Paediatric Gastroenterology Children's Hospital of Wales Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Kotecha","sequence":"additional","affiliation":[{"name":"Department of Child Health Cardiff University School of Medicine Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WJ","family":"Watkins","sequence":"additional","affiliation":[{"name":"Department of Child Health Cardiff University School of Medicine Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HR","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Department of Paediatric Gastroenterology Children's Hospital of Wales Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200012030-00013"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2012-301885.1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i32.3665"},{"key":"e_1_2_9_5_1","first-page":"136","article-title":"ESPHGAN Guidelines for the diagnosis of coeliac disease in children and adolescents: an evidenced based approach","volume":"54","author":"Husby S","year":"2012","journal-title":"JPGN"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.40.1.61"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2008.03871.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2005.02.005"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890701678689"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2012.01.006"},{"key":"e_1_2_9_11_1","unstructured":"LewisNR.Is the diagnosis of coeliac disease associated with socioeconomic status? 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