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Retinal vessel morphology was evaluated at mean postnatal age 7\u00a0days. Insulin\u2010like growth factor\u2010I (<jats:styled-content style=\"fixed-case\">IGF<\/jats:styled-content>\u2010I) levels were analysed in umbilical cord blood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 78 infants, 21 (27%) had abnormal retinal vessel morphology; they had significantly lower median (range) birth weight [1850\u00a0g, (1190\u20133260), vs. 2320, (1330\u20133580), p\u00a0&lt;\u00a00.0001], shorter birth length [43.0\u00a0cm, (38\u201349), vs. 46.0, (40\u201350), p\u00a0&lt;\u00a00.0001] and smaller head circumference [31.0\u00a0cm, (27.7\u201334.0), vs. 32.0, (27.5\u201336.5), p\u00a0=\u00a00.003]. They also had significantly lower gestational age [34\u00a0+\u00a01\u00a0weeks, (32\u00a0+\u00a02\u201335\u00a0+\u00a03), vs. 34\u00a0+\u00a06, (32\u00a0+\u00a02\u201336\u00a0+\u00a06), p\u00a0=\u00a00.004] and mean\u00a0\u00b1\u00a0<jats:styled-content style=\"fixed-case\">SD IGF<\/jats:styled-content>\u2010I levels (24.6\u00a0\u00b1\u00a017.0\u00a0<jats:italic>\u03bc<\/jats:italic>g\/L vs. 46.7\u00a0\u00b1\u00a021.5, p\u00a0&lt;\u00a00.0001). A higher percentage of these infants were small for gestational age (57.1% vs. 15.8%, p\u00a0=\u00a00.001), and maternal hypertension\/preeclampsia rates were also higher (47.6% vs. 19.3%, p\u00a0=\u00a00.03). Step\u2010wise logistic regression showed that birth weight was the strongest predictor of abnormal retinal vascularisation (p\u00a0&lt;\u00a00.0001, odds ratio 0.040, 95% confidence interval 0.007\u20130.216).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this population of moderately to late preterm newborns, birth weight appeared to affect the retinal vascular system.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12599","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T11:53:43Z","timestamp":1392638023000},"page":"594-600","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Birth weight is the most important predictor of abnormal retinal vascularisation in moderately preterm infants"],"prefix":"10.1111","volume":"103","author":[{"given":"K","family":"Allvin","sequence":"first","affiliation":[{"name":"Gothenburg Pediatric Growth Research Center (GP\u2010GRC) Institute of Clinical Sciences Sahlgrenska Academy at the University of Gothenburg and The Queen Silvia Children's Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Hellstr\u00f6m","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Physiology\/Ophthalmology Sahlgrenska Academy at the University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Dahlgren","sequence":"additional","affiliation":[{"name":"Gothenburg Pediatric Growth Research Center (GP\u2010GRC) Institute of Clinical Sciences Sahlgrenska Academy at the University of Gothenburg and The Queen Silvia Children's Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Andersson Gr\u00f6nlund","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Physiology\/Ophthalmology Sahlgrenska Academy at the 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