{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T05:45:01Z","timestamp":1696571101680},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Mild wheezing during respiratory infections is a common cause of paediatric hospital admissions. This study aimed to identify factors predicting this condition in children over six months of age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed the medical records of 539 children, aged 6\u00a0months to 16\u00a0years, who visited the emergency department because of wheezing during respiratory infection. Mild disease was defined as hospital stays of less than 48\u00a0h and severe disease was staying at least 48\u00a0h or being treated in intensive care. Patients with an initial oxygen saturation value (SaO<jats:sub>2<\/jats:sub>) below\u00a090% were analysed separately.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most (87%) of the 539 patients had mild disease, 6% had a severe disease and 7% had an initial SaO<jats:sub>2<\/jats:sub> below 90%. The area under the receiver operating characteristic (<jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>) curve for the initial SaO<jats:sub>2<\/jats:sub> predicting mild disease was 0.75 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.53\u20130.97), and the optimal cut\u2010off value was 93%. An initial SaO<jats:sub>2<\/jats:sub> &gt;93% had a negative predictive value of 93%. Although 270 patients (50%) were hospitalised, only 140 (26%) would have been admitted using an optimal cut\u2010off of SaO<jats:sub>2<\/jats:sub> \u226493%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>An initial SaO<jats:sub>2<\/jats:sub> &gt;93% reflects a mild course of acute wheezing and using this cut\u2010off point could have almost halved hospital admissions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12688","type":"journal-article","created":{"date-parts":[[2014,5,13]],"date-time":"2014-05-13T15:51:51Z","timestamp":1399996311000},"page":"951-956","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Initial oxygen saturation values can predict the need to hospitalise children with mild wheezing"],"prefix":"10.1111","volume":"103","author":[{"given":"H","family":"Pruikkonen","sequence":"first","affiliation":[{"name":"Department of Paediatrics University of Oulu University Hospital 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