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This literature review examined the pattern and management of severe hyperbilirubinaemia in low\u2010 and middle\u2010income countries (<jats:styled-content style=\"fixed-case\">LMIC<\/jats:styled-content>s) where G6<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> deficiency was 10% or more and found that it was frequently associated with neonatal mortality and, or, neurodevelopmental disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Low\u2010 and middle\u2010income countries need to pay urgent attention to G6<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> deficiency to curtail the preventable burden of jaundice\u2010related morbidity, mortality and disability.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12735","type":"journal-article","created":{"date-parts":[[2014,7,3]],"date-time":"2014-07-03T08:32:22Z","timestamp":1404376342000},"page":"1102-1109","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Addressing the burden of neonatal hyperbilirubinaemia in countries with significant glucose\u20106\u2010phosphate dehydrogenase deficiency"],"prefix":"10.1111","volume":"103","author":[{"given":"Bolajoko O.","family":"Olusanya","sequence":"first","affiliation":[{"name":"Centre for Healthy Start Initiative Ikoyi, Lagos Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abieyuwa A.","family":"Emokpae","sequence":"additional","affiliation":[{"name":"Massey Street Children's Hospital Lagos Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara G.","family":"Zamora","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Minnesota Minneapolis MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina M.","family":"Slusher","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Minnesota &amp; Hennepin County Medical Center Minneapolis MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,15]]},"reference":[{"key":"e_1_2_18_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2915"},{"key":"e_1_2_18_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60106-3"},{"key":"e_1_2_18_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001339"},{"key":"e_1_2_18_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2008.12.005"},{"key":"e_1_2_18_6_1","first-page":"601","article-title":"Glucose\u20106\u2010phosphate dehydrogenase deficiency","volume":"67","author":"WHO Working Group","year":"1989","journal-title":"Bull World Health Organ"},{"key":"e_1_2_18_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60073-2"},{"key":"e_1_2_18_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.inhe.2009.11.001"},{"key":"e_1_2_18_9_1","unstructured":"National Institute for Health and Clinical Excellence.Neonatal jaundice. 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