{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:45:08Z","timestamp":1790700308740,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T00:00:00Z","timestamp":1408060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"ALF, Sweden","award":["No number"],"award-info":[{"award-number":["No number"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      Although cytomegalovirus (\n                      <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                      ) is the most common congenital infection, existing research has not provided us with a full picture of how this can affect children in the future. The aim of this case\u2013control study was to evaluate disabilities in a well\u2010defined group of children with congenital cytomegalovirus (\n                      <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                      ) infection, who had been fitted with cochlear implants because of severe hearing impairment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A multidisciplinary team assessed 26 children with congenital\n                      <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                      infection for balance difficulties, neurodevelopmental disabilities and language and visual impairment. We also included a control group of 13 children with severe hearing impairment due to connexin 26 mutations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The majority of the children with congenital\n                      <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                      infection (88%) displayed balance disturbances, including walking at a later age, but there were no cases in the control group. The\n                      <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                      group also displayed frequent neurodevelopmental disabilities and feeding difficulties.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Congenital\n                      <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                      infection affects the general development of the brain and gives rise to a complex pattern of difficulties. Identifying comorbid conditions is very important, as children with associated difficulties and disabilities need more support than children with just hearing impairment. Congenital\n                      <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                      infection needs to be considered in children with hearing impairment and\/or balance disturbance and\/or neurodevelopmental disabilities.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.12745","type":"journal-article","created":{"date-parts":[[2014,7,11]],"date-time":"2014-07-11T03:14:00Z","timestamp":1405048440000},"page":"1165-1173","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Impaired balance and neurodevelopmental disabilities among children with congenital cytomegalovirus infection"],"prefix":"10.1111","volume":"103","author":[{"given":"Eva","family":"Karltorp","sequence":"first","affiliation":[{"name":"Department of Clintec Karolinska Institutet Stockholm Sweden"},{"name":"Department of Otorhinolaryngology Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrika","family":"L\u00f6fkvist","sequence":"additional","affiliation":[{"name":"Department of Clintec Karolinska Institutet Stockholm Sweden"},{"name":"Department of Speech and Language Pathology Karolinska University Hospital Stockholm Sweden"},{"name":"HEAD Graduate School Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilona","family":"Lewensohn\u2010Fuchs","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Karolinska Institutet Stockholm Sweden"},{"name":"Division of Clinical Microbiology Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Lindstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Clintec Karolinska Institutet Stockholm Sweden"},{"name":"Division of Pediatrics Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mimmi","family":"Eriksson Westblad","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Te\u00e4r Fahnehjelm","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"},{"name":"Department of Pediatric Ophthalmology and Strabismus St Erik Eye Hospital Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Verrecchia","sequence":"additional","affiliation":[{"name":"Department of Clintec Karolinska Institutet Stockholm Sweden"},{"name":"Department of Audiology and Neurotology Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona\u2010Lisa","family":"Engman","sequence":"additional","affiliation":[{"name":"Department of Clintec Karolinska Institutet Stockholm Sweden"},{"name":"Division of Pediatrics Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.544"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2007.09.004"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1748054"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2010.07.026"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182814d2c"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812441572"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365549950163969"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1067\/mpa.2000.103870"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20120710-03"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.01852.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2011.653442"},{"key":"e_1_2_9_13_1","first-page":"370","article-title":"Evaluation of intellectual development of children following congenital, mildly symptomatic cytomegalovirus (CMV) infection. 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