{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:36:46Z","timestamp":1780731406101,"version":"3.54.1"},"reference-count":19,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T00:00:00Z","timestamp":1412640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study evaluated the impact of blood sampling via peripheral arterial catheters on cerebral oxygenation and blood volume as a function of blood sampling velocity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Near\u2010infrared spectroscopy was applied to 20 very low\u2010birthweight infants during peripheral arterial blood sampling. Changes in cerebral oxygenated, deoxygenated and total haemoglobin, cerebral blood volume and cerebral oxygenation index were recorded. Heart rate and oxygen saturation were measured continuously. To assess the impact of blood sampling velocity, both fast 40\u2010sec and slow 70\u2010sec sampling procedures were performed in a crossover study design, in which the order of sampling velocities was randomised for each patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both fast and slow blood sampling procedures resulted in a significant decrease in cerebral oxygenation index (fast, p\u00a0=\u00a00.002, slow, p\u00a0=\u00a00.008), and an increase in mean heart rate (both p\u00a0=\u00a00.02) and mean blood pressure (p\u00a0=\u00a00.02 and 0.04). Oxygenated and total haemoglobin and cerebral blood volume only decreased significantly after slow blood sampling (p\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Blood sampling from peripheral arterial catheters leads to significant fluctuations in cerebral oxygenation independent of the sampling velocity. Changes are comparable to those reported from umbilical blood sampling. We advise that blood sampling should be restricted as much as possible.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12805","type":"journal-article","created":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T11:48:06Z","timestamp":1410781686000},"page":"1227-1232","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Blood sampling via a peripheral artery catheter decreases cerebral oxygenation index in very low\u2010birthweight infants"],"prefix":"10.1111","volume":"103","author":[{"given":"Katrin","family":"Mehler","sequence":"first","affiliation":[{"name":"Department of Neonatology University of Cologne Children\u2032s Hospital Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mareike","family":"Nowak","sequence":"additional","affiliation":[{"name":"Department of Cardiology D\u00fcren Community Hospital Cologne 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