{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T06:02:19Z","timestamp":1778565739060,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,3,13]],"date-time":"2015-03-13T00:00:00Z","timestamp":1426204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to examine the association between allergic bronchopulmonary aspergillosis (<jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content>) and poorly controlled asthma in children and appraise the diagnostic criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included 100 children with poorly controlled asthma. We diagnosed <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> using the <jats:italic>Aspergillus<\/jats:italic> skin test, pulmonary function test, total and specific immunoglobulin E (IgE) to <jats:italic>Aspergillus fumigatus,<\/jats:italic> chest radiograph and high\u2010resolution computed tomography. Patients were diagnosed and classified according to the Rosenberg\u2013Patterson criteria for <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content>. The cut\u2010off value for total serum IgE was calculated by receiver operating characteristics curve analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 100 children with poorly controlled asthma, 26 patients were <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> positive. There was a significant difference in the forced expiratory volume in 1\u2010sec\/forced vital capacity ratio between <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> positive (0.78\u00a0\u00b1\u00a00.14) and negative (0.87\u00a0\u00b1\u00a00.15) children (p\u00a0=\u00a00.008). <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> positive children were categorised as seropositive, central bronchiectasis and other radiological findings. The receiver operating characteristics curve was constructed, and a value of 1200\u00a0<jats:styled-content style=\"fixed-case\">IU<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content> of total IgE was observed, with 88.5% sensitivity and 70.5% specificity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study showed an association between <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> and poorly controlled asthma in children and suggests a higher cut\u2010off value of total IgE for the diagnosis of <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12930","type":"journal-article","created":{"date-parts":[[2015,1,25]],"date-time":"2015-01-25T10:40:54Z","timestamp":1422182454000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["The diagnostic criteria for allergic bronchopulmonary aspergillosis in children with poorly controlled asthma need to be re\u2010evaluated"],"prefix":"10.1111","volume":"104","author":[{"given":"Meenu","family":"Singh","sequence":"first","affiliation":[{"name":"Advanced Pediatric Centre Post Graduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subhamoy","family":"Das","sequence":"additional","affiliation":[{"name":"Advanced Pediatric Centre Post Graduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Advanced Pediatric Centre Post Graduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nandini","family":"Paul","sequence":"additional","affiliation":[{"name":"Advanced Pediatric Centre Post Graduate Institute 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