{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T16:38:27Z","timestamp":1776271107651,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,3,9]],"date-time":"2015-03-09T00:00:00Z","timestamp":1425859200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study explored neonatal morbidity and mortality in hospitalised patients in central Vietnam and risk factors associated with mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a prospective cohort study of all newborn infants (&lt;28\u00a0days) hospitalised in a neonatal unit over a 1\u2010year period and followed until discharge. The main outcome measures were case fatality rate and the rate of different clinical diagnoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 2555 admissions during the study period. The leading primary causes of admissions were infections (41%), haematological problems such as jaundice (23%) and prematurity and its complications (18%). The overall case fatality rate was 8.6%, and it was 59% among very low\u2010birthweight (&lt;1500\u00a0g) neonates. Mortality was inversely associated with birthweight and gestational age. Of the 220 deaths, 57% occurred within the first 7\u00a0days of life. Although the causes of death were often multifactorial, the leading primary causes were infections (32%), prematurity and its complications (25%), birth defects (24%) and birth asphyxia (6%). Risk factors associated with death were being outborn, early gestational age, small for gestational age, confirmed sepsis and birth defects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Mortality rates were high among hospitalised neonates in central Vietnam, and this paper suggests interventions that might improve outcomes<jats:bold>.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.12960","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T16:23:33Z","timestamp":1422980613000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Morbidity and mortality in hospitalised neonates in central Vietnam"],"prefix":"10.1111","volume":"104","author":[{"given":"Hoang T.","family":"Tran","sequence":"first","affiliation":[{"name":"Neonatal Unit Department of Paediatrics Da Nang Hospital for Women and Children Da Nang Vietnam"},{"name":"Centre for International Child Health University of Melbourne Department of Paediatrics and Murdoch Childrens Research Institute Royal Children's Hospital Melbourne Vic. 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Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na M.","family":"Dang","sequence":"additional","affiliation":[{"name":"Neonatal Unit Department of Paediatrics Da Nang Hospital for Women and Children Da Nang Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen M.","family":"Graham","sequence":"additional","affiliation":[{"name":"Centre for International Child Health University of Melbourne Department of Paediatrics and Murdoch Childrens Research Institute Royal Children's Hospital Melbourne Vic. Australia"},{"name":"Department of Paediatrics University of Melbourne Melbourne Vic. 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