{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T04:38:57Z","timestamp":1780547937800,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T00:00:00Z","timestamp":1445990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study prospectively evaluated neuropsychological functioning in 8\u2010year\u2010old patients with anorectal malformation (<jats:styled-content style=\"fixed-case\">ARM<\/jats:styled-content>) and Hirschsprung's disease (<jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>School functioning and behaviour were assessed in a standardised interview. Intelligence, attention, self\u2010esteem and quality of life were evaluated with validated tests and questionnaires. The following predictors were assessed: socio\u2010economic status, number of episodes of general anaesthesia, laxative treatment and premature birth. Severely intellectually disabled patients were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, twelve of the 23 (52%) patients with <jats:styled-content style=\"fixed-case\">ARM<\/jats:styled-content> and 11 (55%) of the 20 patients with <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> received special education or remedial teaching. The intelligence quotient was normal: mean (standard deviation or <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) was 98 (17) and 96 (17), respectively. However, sustained attention was below the norm: mean (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) Z\u2010score was \u22121.90 (1.94) and \u22121.43 (1.98) for <jats:styled-content style=\"fixed-case\">ARM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> patients; both p &lt; 0.01. Self\u2010esteem was normal: mean (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) Z\u2010score was 0.10 (1.29) and \u22120.20 (1.11) for <jats:styled-content style=\"fixed-case\">ARM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> patients. Quality of life was normal in <jats:styled-content style=\"fixed-case\">ARM<\/jats:styled-content> patients and slightly impaired in <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> patients. No predictors for neuropsychological outcome were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite normal intelligence, more than half of these patients received special education or remedial teaching. In addition, problems with sustained attention were found. These findings are important for long\u2010term care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13154","type":"journal-article","created":{"date-parts":[[2015,8,19]],"date-time":"2015-08-19T08:07:00Z","timestamp":1439971620000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Children with congenital colorectal malformations often require special education or remedial teaching, despite normal intelligence"],"prefix":"10.1111","volume":"105","author":[{"given":"Desiree","family":"van den Hondel","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery Erasmus MC \u2013 Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Femke K.","family":"Aarsen","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Erasmus MC \u2013 Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene M.H.","family":"Wijnen","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Erasmus MC \u2013 Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelius E.J.","family":"Sloots","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Erasmus MC \u2013 Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5824-3492","authenticated-orcid":false,"given":"Hanneke","family":"IJsselstijn","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Erasmus MC \u2013 Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.10.048"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.10.022"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.04.025"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000326"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2012.09.068"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.09.006"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.23954"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(00)90215-X"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579406060135"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.118133"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1038325"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.12.034"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.08.002"},{"key":"e_1_2_10_15_1","unstructured":"Centraal Bureau voor de Statistiek (Statistics Netherlands). 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