{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:42:04Z","timestamp":1789454524160,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,10,10]],"date-time":"2015-10-10T00:00:00Z","timestamp":1444435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006285","name":"Magnus Bergvalls Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      This study investigated if skin\u2010to\u2010skin contact could provide pain relief, measured with near\u2010infrared spectroscopy (\n                      <jats:styled-content style=\"fixed-case\">NIRS<\/jats:styled-content>\n                      ), during venepuncture in premature infants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Ten infants born at 26\u201335 weeks of gestation were examined during a blood\u2010sampling procedure with venepuncture under two different conditions: in skin\u2010to\u2010skin contact with their mother or lying in their incubator or crib. A double\u2010channel\n                      <jats:styled-content style=\"fixed-case\">NIRS<\/jats:styled-content>\n                      device was used, and oxygen saturation and heart rate were measured using pulse oximetry. The infant's face and the pulse oximetry values were videotaped throughout the procedures, so that we could carry out a pain assessment using the Premature Infant Pain Profile\u2010Revised (\n                      <jats:styled-content style=\"fixed-case\">PIPP<\/jats:styled-content>\n                      \u2010R).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We found a significantly smaller increase in oxygenated haemoglobin on the contralateral side during venepuncture when the infants were in skin\u2010to\u2010skin contact with their mothers, compared to when they were laying in their incubator or crib. When venepuncture was compared with a sham procedure, oxygenated haemoglobin increased significantly more with the infant in the incubator or crib than held skin\u2010to\u2010skin, but no significant differences could be seen in the\n                      <jats:styled-content style=\"fixed-case\">PIPP<\/jats:styled-content>\n                      \u2010R results between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study showed that skin\u2010to\u2010skin contact between premature infants and their mothers during venepuncture had a pain\u2010relieving effect.<\/jats:p>\n                  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