{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T11:10:23Z","timestamp":1761217823611},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,1,8]],"date-time":"2016-01-08T00:00:00Z","timestamp":1452211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Following the elective ventilation and referral for organ donation of an infant with anencephaly, we sought local perinatal professionals\u2019 views of this practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Anonymous online survey: demographics, ethical viewpoints and potential public\/maternal perceptions (standard 5\u2010part Likert scale and free text).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Demographics: 49 replies (38 female): 4 obstetricians, 14 neonatologists, 6 foetal clinicians, 23 nurses, 1 anaesthetist and 1 reproductive specialist. Experience: 0.5\u201333 years (average 12). Twenty\u2010one had experience of anencephalic delivery, and 10 reported pregnancy continued for religious reasons. Ethics: (i) 73% thought anencephalic donation acceptable, of which 64% supported elective ventilation, 20% neutral and 16% disagreed. (ii) Provision of treatments not in infant's strict best interest to facilitate donation: 22% strongly agreed, 36% agreed, 33% neutral and 9% disagreed. (iii) Accept ventilation to permit donation if societal benefit: 53% agreed, 33% neutral and 13% disagreed. (iv) Public opinion: 59% disagreed anencephalic donation would harm public opinion about donation and 19% agreed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found a supportive local environment for donation in the setting of anencephaly, including support for elective ventilation. Given this, and our ethical analysis, we recommend provision of organ donation information as part of palliative care counselling for women carrying a foetus with a condition likely to be fatal in infancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13281","type":"journal-article","created":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T13:42:05Z","timestamp":1450273325000},"page":"494-498","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Elective ventilation to facilitate organ donation in infants with anencephaly: perinatal professionals\u2019 views and an ethical analysis"],"prefix":"10.1111","volume":"105","author":[{"given":"Alisa","family":"Jivraj","sequence":"first","affiliation":[{"name":"St Georges Medical School University of London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angie","family":"Scales","sequence":"additional","affiliation":[{"name":"Critical Care Unit Great Ormond Children's Hospital London UK"},{"name":"NHS Blood and Transplant Bristol UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joe","family":"Brierley","sequence":"additional","affiliation":[{"name":"Critical Care Unit Great Ormond Children's Hospital London UK"},{"name":"Paediatric Bioethics Centre Great Ormond St Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,8]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"BottingB.Trends in Neural Tube Defects. 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Available at:http:\/\/www.dailymail.co.uk\/health\/article-3051430\/Britain-s-youngest-organ-donor-Parents-tell-heartbreaking-decision-donate-kidneys-heart-valves-hero-twin-son-Teddy-lived-100-minutes.html#ixzz3eRjhwFmG. (accessed on June 2015)"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02380.x"},{"key":"e_1_2_9_12_1","unstructured":"RCPCH Working group.The diagnosis of death by neurological criteria (DNC) in infants less than two months old. London April 2015. 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