{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:00:34Z","timestamp":1790524834041,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T00:00:00Z","timestamp":1454976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study assesses the association between pesticide exposure in pregnancy, preterm birth (<jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content>) and shortened gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pregnancy information was abstracted from the Centers for Disease Control (<jats:styled-content style=\"fixed-case\">CDC<\/jats:styled-content>) Non\u2010Public Use Natality Datasets 1990\u20132005. Pesticide use in maternal county of residence was calculated using California Pesticide Use Reporting (<jats:styled-content style=\"fixed-case\">PUR<\/jats:styled-content>) data 1990\u20132005. Counties were ranked by pesticide use, and birth months were sorted by <jats:italic>peak<\/jats:italic> (May\u2013June) or <jats:italic>nonpeak<\/jats:italic> (other months) pesticide use. Multivariate logistical regression models were used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Counties with higher pesticide use were associated with higher <jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> (<jats:italic>low<\/jats:italic> 8.59\u00a0\u00b1\u00a00.11%, <jats:italic>moderate<\/jats:italic> 9.25\u00a0\u00b1\u00a00.07%, <jats:italic>high<\/jats:italic> 10.0\u00a0\u00b1\u00a00.06%, p's\u00a0&lt;\u00a00.001) and shorter gestations (<jats:italic>low<\/jats:italic> 39.197\u00a0\u00b1\u00a00.014\u00a0weeks, <jats:italic>moderate<\/jats:italic> 39.126\u00a0\u00b1\u00a00.011\u00a0weeks, <jats:italic>high<\/jats:italic> 39.049\u00a0\u00b1\u00a00.011\u00a0weeks, p's\u00a0&lt;\u00a00.001). Peak pesticide months were associated with higher <jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> (10.01\u00a0\u00b1\u00a00.05% vs. 9.36\u00a0\u00b1\u00a00.05%, p\u00a0&lt;\u00a00.001) and shorter gestations (39.069\u00a0\u00b1\u00a00.007\u00a0weeks vs. 39.122\u00a0\u00b1\u00a00.007\u00a0weeks, p\u00a0&lt;\u00a00.001). The pesticide effect on shortened gestation and higher <jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> was found in all racial groups. Pesticide use was highest for fungicides &gt; insecticides &gt; fumigants &gt; herbicides &gt; others. Each pesticide type was found to be associated with higher <jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> and shorter gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PTB<\/jats:styled-content> and shortened gestation were significantly associated with pesticide use in maternal county of residence regardless of race, gestation at birth, and in most risk categories.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13288","type":"journal-article","created":{"date-parts":[[2015,11,27]],"date-time":"2015-11-27T14:22:46Z","timestamp":1448634166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["County\u2010level pesticide use and risk of shortened gestation and preterm birth"],"prefix":"10.1111","volume":"105","author":[{"given":"Paul","family":"Winchester","sequence":"first","affiliation":[{"name":"Section\u00a0of Neonatal\u2010Perinatal Medicine Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy","family":"Proctor","sequence":"additional","affiliation":[{"name":"Section\u00a0of Neonatal\u2010Perinatal Medicine Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Ying","sequence":"additional","affiliation":[{"name":"Department of Environmental Health University of Cincinnati College of Medicine Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0860"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwp413"},{"key":"e_1_2_10_4_1","first-page":"17","volume-title":"National vital statistics report, births: final data for 2006","author":"Martin JA","year":"2009"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181cbd5f5"},{"key":"e_1_2_10_6_1","first-page":"790","volume-title":"Preterm birth: causes, consequences, and prevention","author":"Behrman RE","year":"2007"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.6789"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.0900784"},{"key":"e_1_2_10_9_1","unstructured":"California Department of Pesticide Regulation.California Pesticide Use Reports [Internet] 1990\u20132005. Available at:http:\/\/www.cdpr.ca.gov\/docs\/pur\/purmain.htm(accessed on July 23 2009)."},{"key":"e_1_2_10_10_1","unstructured":"CDC\/National Center for Health Statistics.U.S. Natality Non\u2010Public Use Data Files and Documentation. 1990\u20132005."},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009231"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2011.04.015"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwt313"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1002775"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.8051"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0031901"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-1058"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.11338"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph8041061"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042275"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.02.065"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025254"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.041431898"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapa.13288","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.13288","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/apa.13288","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.13288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T05:43:06Z","timestamp":1694410986000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.13288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,9]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1111\/apa.13288"],"URL":"https:\/\/doi.org\/10.1111\/apa.13288","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,9]]},"assertion":[{"value":"2015-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-11-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-02-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}