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Our research identifies tissue\u2010specific mechanisms underlying foetal growth restriction and then tests strategies to improve growth and ameliorate many of the metabolic problems before the infant is born. The goal of our studies is to reduce the impact of foetal growth restriction at critical stages of development on the lifelong complications of <jats:styled-content style=\"fixed-case\">IUGR<\/jats:styled-content> offspring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Defining specific mechanisms that cause growth restriction in the foetus might identify specific nutrients and hormones that could be given to the mother to improve foetal growth and reduce metabolic complications, using strategies first tested in our <jats:styled-content style=\"fixed-case\">IUGR<\/jats:styled-content> animal model.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13413","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T00:11:32Z","timestamp":1459383092000},"page":"881-889","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Challenges in nourishing the intrauterine 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