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The presence and location of <jats:styled-content style=\"fixed-case\">SCFN<\/jats:styled-content> were recorded at the time of discharge or at follow\u2010up visits. To identify the risk factors for developing <jats:styled-content style=\"fixed-case\">SCFN<\/jats:styled-content>, we compared the perinatal characteristics of those newborns who developed <jats:styled-content style=\"fixed-case\">SCFN<\/jats:styled-content> with those who did not.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The newborns developing <jats:styled-content style=\"fixed-case\">SCFN<\/jats:styled-content> had significantly higher birthweights compared with those newborns who did not develop <jats:styled-content style=\"fixed-case\">SCFN<\/jats:styled-content>. Among the newborns with a birthweight equal or superior to the 90th percentile, those who developed <jats:styled-content style=\"fixed-case\">SCFN<\/jats:styled-content> had a significantly higher use of inotropic support and higher maximum troponin levels during their initial hospitalisation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A higher birthweight represented an independent risk factor for developing <jats:styled-content style=\"fixed-case\">SCFN<\/jats:styled-content> in asphyxiated newborns treated with hypothermia. When macrosomia is present, other risk factors related to haemodynamic instability during the initial hospitalisation may also increase the risk of developing <jats:styled-content style=\"fixed-case\">SCFN<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13463","type":"journal-article","created":{"date-parts":[[2016,5,5]],"date-time":"2016-05-05T14:12:50Z","timestamp":1462457570000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Macrosomia and haemodynamic instability may represent risk factors for subcutaneous fat necrosis in asphyxiated newborns treated with hypothermia"],"prefix":"10.1111","volume":"105","author":[{"given":"C","family":"Courteau","sequence":"first","affiliation":[{"name":"Division of Newborn Medicine Department of Pediatrics McGill University Montreal QC 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